Human Biology (MindTap Course List)
11th Edition
ISBN: 9781305112100
Author: Cecie Starr, Beverly McMillan
Publisher: Cengage Learning
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Textbook Question
Chapter 22, Problem 6SQ
Tumor suppressor genes _____.
- a. occur normally in cells
- b. promote metastasis
- c. are brought into cells by viruses
- d. only rarely affect the development of cancer
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Sometimes, malignant cells do not stay properly anchored in tissues because of the loss of function of:
a.
cell walls
b.
oncogenes
c.
plasma membrane adhesion proteins
d.
nuclear membranes
e.
tumor suppressor genes
A tumor suppressor gene ___regulates the cell cycle; an example is _____.
Select one:
a.
negatively, cyclin
b.
positively, retinoblastoma
c.
positively, p21
d.
negatively, retinoblastoma
e.
positively, RAS
Which of the following is NOT an example of fail-safe mechanisms that prevent the irregular cell divisions characteristic of cancer?
a.Shortening of telomeres
b.Cell division limit
c.Mutation in a tumor suppressor gene
d.Triggered cell death
Chapter 22 Solutions
Human Biology (MindTap Course List)
Ch. 22 - Prob. 1RQCh. 22 - Prob. 2RQCh. 22 - Prob. 3RQCh. 22 - Prob. 4RQCh. 22 - Prob. 5RQCh. 22 - Prob. 6RQCh. 22 - Prob. 1SQCh. 22 - Prob. 2SQCh. 22 - Prob. 3SQCh. 22 - Prob. 4SQ
Ch. 22 - Prob. 5SQCh. 22 - Tumor suppressor genes _____. a. occur normally in...Ch. 22 - Prob. 7SQCh. 22 - The most common therapeutic approaches to treating...Ch. 22 - Prob. 9SQCh. 22 - Prob. 10SQCh. 22 - Prob. 1CTCh. 22 - A textbook on cancer contains the following...Ch. 22 - Ultimately, cancer kills because it spreads and...Ch. 22 - Over the last few months, your best friend, Mark,...Ch. 22 - Some desperate cancer patients consume pills or...
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- Cancer causing genes are called ________. a. transformation genes b. tumor suppressor genes c. oncogenes d. mutated genesarrow_forwardTumor Suppressor Genes are often called as gatekeepers because: a. They signify their involvement in governing the dynamics of cell proliferation b. They allow tumors to proliferate at an uncontrolled rate c. To allow a transport channel of suppressors d. They are not referred to as ?gatekeepers?arrow_forwardWhich of the following traits are common to many cancer cells (more than one answer may be correct)A. Uncontrolled growth and divisionB. Chromosomes abnormalitiesC. Absence of a cytoskeletonD. Decreased adhesion to other cellsarrow_forward
- Which of the following is typical of cancer cells? A. The parent cell of the tumor contains a single mutation in a single checkpoint gene. B. Malignant cells migrate. C. Cancer cells lose the ability to divide. D. Products of oncogenes inhibit mitosis E. Benign tumors invade normal tissue.arrow_forwardWith regard to cancer cells, which of the following statementsare true?A. Cancer cells are clonal, which means they are derived from asingle mutant cell.B. To become cancerous, cells usually accumulate multiplegenetic changes that eventually result in uncontrolledgrowth.C. Most cancers are caused by oncogenic viruses.D. Cancer cells have lost the ability to properly regulate celldivision.arrow_forward________ are changes to the nucleotides in a segment of DNA that codes for a protein. a. Proto-oncogenes b. Tumor suppressor genes c. Gene mutations d. Negative regulatorsarrow_forward
- Another model, the random model, proposes that any cell in a malignant tumor has the potential to form a new tumor. Does the cancer stem cell hypothesis contradict this idea?arrow_forwardSome types of cancers are treated with surgery, chemotherapy, stem cell replacement or radiation, similar to ultraviolet light. Why might it be beneficial to irradiate cancer cells? Choose the Best answer. A. it kills off all the cancer cells. B. it forces all cancer cells into G0 C. it will halt cell division and possibly be forced into apoptosis D. it could kill off the cancer cells, halt cell division or possibly force the cell into apoptosisarrow_forwardA tumor suppressor gene regulates the cell cycle; an example is . Select one: a. positively, p21 b. negatively, cyclin c. positively, retinoblastoma d. negatively, retinoblastoma e. positively, RAS Cycle HW due Jump to. 4) Next pa cancer stem cellsarrow_forward
- Much remains unknown about the rapid, uncontrolled growth, or what causes a tumor to metastasize. Scientists do know that cancer cells come from normal healthy cells that have had some type of damage done to the genes that aid in the production of the regulatory proteins for the cell cycle. What causes this damage? a proto-oncogenes b mutations c enzymes d tumor suppressorsarrow_forwardHypermethylation is thought to contribute to cancer by a. inhibiting DNA replication. b. inhibiting the expression of tumor-suppressor genes. c. stimulating the translation of oncogenes. d. stimulating telomerase.arrow_forwardNormal (nonmutant) tumor-suppressor genes often functiona. as negative regulators of cell division.b. in the maintenance of genome integrity.c. in the stimulation of cell division.d. as both a and b.arrow_forward
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