Human Biology (MindTap Course List)
11th Edition
ISBN: 9781305112100
Author: Cecie Starr, Beverly McMillan
Publisher: Cengage Learning
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Chapter 22, Problem 3SQ
Summary Introduction
Introduction: Cancer is caused by abnormal uncontrolled cell growth. This occurs due to several genetic and epigenetic alterations that cause uncontrolled proliferation of cells. The clinical manifestations of cancer are numerous, and depend on the variety and intensity of symptoms.
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True or false: When oncogenes are present, a cell is more likely to be normal (non-cancerous) than when they are not present.
The genes for retinoblastoma (pRB) and p53, act as ________ in regulating the cell cycle.
oncogenes
proto-oncogenes
pseudo-oncogenes
tumor enhancer genes
tumor suppressor genes
____________ is the most common tumor suppressor gene that is often mutated in human cancers.
Chapter 22 Solutions
Human Biology (MindTap Course List)
Ch. 22 - Prob. 1RQCh. 22 - Prob. 2RQCh. 22 - Prob. 3RQCh. 22 - Prob. 4RQCh. 22 - Prob. 5RQCh. 22 - Prob. 6RQCh. 22 - Prob. 1SQCh. 22 - Prob. 2SQCh. 22 - Prob. 3SQCh. 22 - Prob. 4SQ
Ch. 22 - Prob. 5SQCh. 22 - Tumor suppressor genes _____. a. occur normally in...Ch. 22 - Prob. 7SQCh. 22 - The most common therapeutic approaches to treating...Ch. 22 - Prob. 9SQCh. 22 - Prob. 10SQCh. 22 - Prob. 1CTCh. 22 - A textbook on cancer contains the following...Ch. 22 - Ultimately, cancer kills because it spreads and...Ch. 22 - Over the last few months, your best friend, Mark,...Ch. 22 - Some desperate cancer patients consume pills or...
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- Cancer is a genetic disease. To provide evidence that you understand cancer genes are altered in both sporadic (somatic) and inherited cancers, match the beginning and end of the sentences below to give correct statements. NOTE: there is one extra, redundant answer, do not use it. This question has partial credit, so you will still be awarded some marks even if all of your sentences are not correct. Prompts Gain of function Oncogenes Mutated forms of proto-oncogenes Examples of oncogenes Loss of function. Examples of tumor suppressor genes Tumor suppressor genes Inherited cancer The Knudson's 2-hit hypothesis Both inherited and sporadic cancers Submitted Answers Choose a match Choose a match Choose a match Choose a match. Choose a match. Choose a match Choose a match. Choose a match. Choose a match Choose a match. ▼ ▼ ▼ O protect cells from uncontrolled proliferation are; CMYC, KRAS & ErBb2 is seen in oncogenes, leading to cancer. involve Tumor suppressor genes are not involved in…arrow_forwardRelatively few inherited forms of cancer involve the inheritance of mutant oncogenes. Instead, most inherited forms of cancer are defects in tumor-suppressor genes. Give two or more reasons why inherited forms of cancer seldom involve activated oncogenes.arrow_forward"In the cellular regulatory pathways that control cell growth and proliferation, the products of oncogenes are stimulatory components and the products of tumor suppressor genes are inhibitory components" is true or false.arrow_forward
- A normally functioning gene that regulates the cell cycle by stopping cell division is most likely to be a(n) __________. Group of answer choices carcino-gene tumor suppressor proto-oncogene muta-gene oncogenearrow_forwardAll of the following are characteristics of oncogenes EXCEPT Multiple Choice they are mutated proto-oncogenes. they cause cancer. they are genes that stimulate uncontrolled cell division. they are tumor suppressor genes.arrow_forwardThe palladin gene, which plays a role in pancreatic cancer (see theintroduction to this chapter), is said to be an oncogene. Which of itscharacteristics suggest that it is an oncogene rather than a tumorsuppressorgene?arrow_forward
- One example of a DNA virus (a virus that uses DNA, not RNA, as its genetic material) that causes tumors is human papillomavirus (HPV). Do some research and explain how HPV inactivates the RB protein and indicate with which type(s) of cancer it is associated. Don’t forget to cite your sources.arrow_forwardExplain why mutations in tumor suppressor genes are recessive (both copies of the gene must be defective for the regulation of cell division to be defective), whereas mutations in oncogenes are dominant.arrow_forwardCancers typically have which of the following in common? Question 1 options: abnormal nuclei become a neuron promote blood vessel formation immortal life span; meaning they can reproduce indefinitely ignore growth regulatorsarrow_forward
- Certain types of cancerous lung tumors can secrete hormones normally made by the pancreas, adrenal gland, and hypothalamus. What prevents such secretion of happening in healthy cells?arrow_forwardBenign tumors: a. are noncancerous growths that do not spread to other tissues b. do not contain mutations c. are malignant and clonal in origin d. metastasize to other tissues e. none of thesearrow_forwardIs the following true or false AND EXPLAIN: Cells with one functional copy of a proto-oncogene will usually proliferate faster than normal cells.arrow_forward
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