Which of the following statements is true? a. Oncogene candidates can include regulatory proteins such as kinases that can be overexpressed due to reciprocal translocations. O b. When a tumor suppressor gene is nonfunctional, cancer is likely regardless of the presence of an oncogene. О с. Germline mutations in tumor suppressor genes do not increase the risk of cancer in individuals because most mutations are recessive. O d. Conversion of a protooncogene into an oncogene generally involves a loss-of-function mutation.
Which of the following statements is true? a. Oncogene candidates can include regulatory proteins such as kinases that can be overexpressed due to reciprocal translocations. O b. When a tumor suppressor gene is nonfunctional, cancer is likely regardless of the presence of an oncogene. О с. Germline mutations in tumor suppressor genes do not increase the risk of cancer in individuals because most mutations are recessive. O d. Conversion of a protooncogene into an oncogene generally involves a loss-of-function mutation.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:Which of the following statements is true?
O a. Oncogene candidates can include regulatory proteins such as kinases that can be overexpressed due to reciprocal
translocations.
O b.
When a tumor suppressor gene is nonfunctional, cancer is likely regardless of the presence of an oncogene.
O C. Germline mutations in tumor suppressor genes do not increase the risk of cancer in individuals because most mutations are
recessive.
O d. Conversion of a protooncogene into an oncogene generally involves a loss-of-function mutation.
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