Which of the following steps are correct about multistep tumorigenesis (select all that apply)? A. Mutations in progenitor cells are more likely to develop a neoplastic state compared to mutations in stem cells B. Driver mutations give a cell clone a proliferative advanage C. The rate of mutation /genetic change is constant during tumor progression D. Nutrition/diet may effect rate of tumorigenesis E. All cells within a tumor are biologically equivalent and equally capable of high levels proliferation
Which of the following steps are correct about multistep tumorigenesis (select all that apply)?
| A. |
Mutations in progenitor cells are more likely to develop a neoplastic state compared to mutations in stem cells |
|
| B. |
Driver mutations give a cell clone a proliferative advanage |
|
| C. |
The rate of mutation /genetic change is constant during tumor progression |
|
| D. |
Nutrition/diet may effect rate of tumorigenesis |
|
| E. |
All cells within a tumor are biologically equivalent and equally capable of high levels proliferation |
When a normal cell undergoes uncontrolled differentiation and division it causes tumor cells. It is a result of abnormal proliferation of the normal cells without controlled cell differentiation and apoptosis. The tumor is also known as a neoplasm. Two types of tumors are benign (neoplastic cells in a clustered form) and malignant (neoplastic cells are invasive).
Step by step
Solved in 4 steps
