somatic tumors cause local regions in their vicinity to have an increased pOH, how is this strategic for the survival of the tumor?

Q: When human hemoglobin undergoes a mutation, the mutant protein usually does not replace all of the…

A: The cytosol of red blood cells contains the oxygen-carrying globular protein hemoglobin, which is…

Q: Contractile force generated by cardiac myocytes is regulated by input from the autonomic nervous…

A: Heart is a conical muscular organ that contracts and pumps blood into the circulation. To function…

Q: the most widely distributed plasma-membrane effector protein in cells is adenylyl cyclase true or…

A: Introduction: Adenosine triphosphate (ATP) is transformed by adenylate cyclase (AC) into…

Q: a. A typical cellular response of a mammary epithelial cell to EGF signal is proliferation. the Kd…

A: Proliferation is the cellular response.

Q: GSK

A: Introduction:- The activities of cyclin -D dependent kinases serves to integrate extracellular…

Q: Which of the following statements are true about the rate of mutation in tumor cells (select all…

A: Chromosome rearrangements, which occur at high rates due to aneuploidy, an aberrant chromosome…

Q: The gamma and beta subunits that make up fetal and adult hemoglobin, respectively, differ in a…

A: BPG is 2,3-bisphosphoglycerate, which produced in the respiring tissue as a byproduct of glucose…

Q: Which of the following classes of oncogenes would likely be druggable with a small molecule (select…

A: Oncogenes are genes that have the potential to cause cancer. They can be found in normal cells and…

Q: Here is a chloride cell in the gill epithelium of a fish. For reference, NKA = Na+/K+ ATPaseNKCC =…

A: The chloride cells are present in the gills of freshwater and seawater fishes. In the seawater fish,…

Q: Proteins found in the blood respond to blood vessel damage by clumping together forming a clot that…

A: Answer : b) Produce and store the clotting protein in an inactive form. When the protein is needed,…

Q: 2. The Ca2+ ATPase pumps on the sarcoplasmic reticulum membrane play an important role in muscle…

A: The calcium-ATPase pumps occur in two types, namely the P type calcium-ATPase and the SERCA…

Q: TSC acts as a tumor suppressor by continually suppressing mTOR and must be inhibited in order for…

A: TSC (Tuberous Sclerosis Complex) acts as a negative regulator of the mTOR (mechanistic target of…

Q: Sickle cell anemia is associated with which of the following:   Question 27 options:   Sticky…

A: Sickle cell anemia : It is caused by the single acidic amino acid substitution, Glu 6th position to…

Q: Scientists have identified overexpression of Na+/K+ ATPases in several types of cancers plorectal…

A: It is given that we have to design a drug which is preventing the overexpression of the Na+/K+…

Q: PDGF is encoded by a gene that can cause cancer when expressed inappropriately. why do cancers not…

A: Platelet-derived growth factor (PDGF) belongs to the class of growth factor proteins. They regulate…

Q: Select all of the statements that apply to transcytosis. A. Transfers dimeric IgG B. Transfers…

A: Introduction :- Transcytosis is the process by which a ligand is taken up by a receptor on one side…

Q: Briefly describe how the cyclin D-cdk4/6 and cyclin E-cdk2 complexes regulate Retinoblastoma protein…

A: Retinoblastoma is the disease occurring in the retina of the eyes. This is basically eye cancer…

Q: One important role of Fas and Fas ligand is to medi-ate the elimination of tumor cells by killer…

A: In multicellular organisms, cell death is mediated by two mechanisms: apoptosis and necrosis.…

Q: VEGF is synthetized in cancer cell to promote angiogenesis. Which sentence is correct

A: VEGF:- VEGF mean Vascular endothelial growth factor, originally known as vascular permeability…

Q: (c) ADP binds to platelets to initiate the activation process. Two binding receptors were identified…

A: Dissociation constant Kd is used to describe the affinity of a receptor to its ligand . It is a…

Q: Basal cell carcinoma arises from inappropriate activation of the Hedgehog pathway. Which of the…

A: Basal cell carcinoma is a type of skin cancer. Basal cell carcinoma begins in the basal cells is a…