Basal cell carcinoma arises from inappropriate activation of the Hedgehog pathway. Which of the following would inhibit basal cell carcinoma formation? HH ---| PTCH1 ---| SMO ---| SUFU ---| GLI O Loss of one copy of PTCH1

Human Anatomy & Physiology (11th Edition)
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ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Basal cell carcinoma arises from inappropriate activation of the Hedgehog pathway.
Which of the following would inhibit basal cell carcinoma formation?
HH ---| PTCH1 ---| SMO ---| SUFU ---| GLI
Loss of one copy of PTCH1
Loss of both copies of SMO
Loss of both copies of SUFU
More HH expression
Constitutive activity of SMO
Transcribed Image Text:Basal cell carcinoma arises from inappropriate activation of the Hedgehog pathway. Which of the following would inhibit basal cell carcinoma formation? HH ---| PTCH1 ---| SMO ---| SUFU ---| GLI Loss of one copy of PTCH1 Loss of both copies of SMO Loss of both copies of SUFU More HH expression Constitutive activity of SMO
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