A microarray is a technique used to develop a profile of the messenger RNA being transcribed by cells at a particular point in the life cycle of the cell. This allows the researcher to detect the expression of particular genes at a particular time. Microarrays have proven very useful in the detection of genes involved in certain types of cancer. If the product of a particular gene functions as a tumor suppressor, which piece of evidence do you think would be the most useful in the diagnosis of a cancer due to a nonsense mutation in this tumor-suppressor gene? (Hint: Don't worry about what a microarray is. Think about what you know about mitosis, cancer, and types of mutation.) O The tissue sample responds to treatment with a mitosis-promoting compound. O The tissue sample shows a high level of gene expression relative to a control (noncancerous) sample. O The mRNAs for the targeted tumor suppressor sequence are not being produced. O The mRNAs for cyclins and kinases show unusually high levels of expression.

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Q: hallmarks of tumor cells

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Q: Which of the following mutations is likely to be associated with development of cancer? Loss of SMO…

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Q: What is the difference between an oncogene and a tumor-suppressor gene? Give some examples of the…

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Q: A SNP array has identified a mutation in a tumor suppressor in a patient’s cancerous tumor. A drug…

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Q: The current way to gauge the effectiveness of chemotherapy is to track the size of the tumor. If the…

A: Introduction : The use of  different combination of drugs in the treatment of cancer is referred to…

Q: What genetic material was used in this research?" 2. How does the completion of this research…

A: Cancer: It is a diseases that occur due to the uncontrolled division of cells. When the normal cells…

Q: A question that puzzled scientists was that how chemical carcinogens caused cancer. The experiment…

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Q: Describe, using specific examples, the differences in how a growth factor gene and a tumor…

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Q: O The RB gene is likely hypomethylated in this individual O This individual is at much higher risk…

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Q: Describe error prone polymerases and the process of translesion synthesis (TLS). In regards to tumor…

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Q: In some cancer cells, a specific gene has been duplicated many times. Is this gene likely to be an…

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Q: RASL11A gene is a tumor suppressor gene associated with spontaneous tumor shrinkage in Tasmanian…

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Q: Which of these events do you think is likely to promote tumorigenesis in affected cells? Group of…

A: Tumorigenesis is the process of forming a tumor, which is an abnormal growth of cells.

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Q: Which type of mutation would NOT be involved in the inactivation of a tumor suppressor gene?

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Q: Which of the following chromosomal changes would be LEAST likely to cause the development of cancer?…

A: Cancer is a condition where cells in a specific part of the body grow and reproduce uncontrollably.…

Q: There are three broad categories of cancer-related genes: proto-oncogenes, tumor suppressor genes,…

A: It is an uncontrollable cell division that get metastasized into surrounding tissues.

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.