Which of the following chromosomal changes would be LEAST likely to cause the development of cancer? a chromosomal deletion of a region containing the tumor suppressor gene duplication of a tumor suppressor gene a loss-of-function mutation in a tumor suppressor gene DNA methylation of the promoter of a tumor suppressor gene a mutation in a regulatory element that disrupts transcription of a tumor suppressor gene

Q: The protein p53 is activated when the cell's DNA is damaged. p53 helps to arrest the cell cycle in…

A: Cell division is controlled by a protein that is encoded by a tumor suppressor gene. Uncontrolled…

Q: Why are some chromosomal regions amplified/deleted in a specific manner in certain tumor types?

A: Chromosomal amplification: Chromosomal amplification can be explained as the increase in the amount…

Q: What is meant by the "two-hit" model of cancer development? Describe this theory in detail and…

A: Two-hit hypothesis : The "two-hit" hypothesis or model was first proposed by geneticist Alfred…

Q: The C-myc gene is a proto-oncogene which is highly expressed in breast tissue and appears to cause…

A: Answer.) :- The ChIP data provided involves key molecular components and factors associated with…

Q: Put a checkmark next to any of the following scenarios that would make it MORE likely that a cell…

A: Need to find all the options that produce uncontrollable cell division  and to increase chance of…

Q: Which genetic cancer predisposition syndrome is caused by germ-line mutations in the p53 gene and is…

A: P53 is the tumor suppressor protein (TP53 in humans) which is also described as the guardian of the…

Q: What is the difference between an oncogene and a tumor-suppressor gene? Give some examples of the…

A: Cell proliferation, cell differentiation, and cell survival are under the control of some critical…

Q: Cancer is a major public health problem.  Both inherited genes and environmental factors play a role…

A: Cancer has become a major global health issue for some time. Cancers occur by environmental…

Q: examine the process of gene expression. Include the following: Explain the regulation of gene…

A: Introduction Gene Expression Is The Process Through Which Information From A Gene Is Used To Create…

Q: Discuss how oncogenes and tumor suppressor genes are related to genes involved in the control of…

A: Tumor suppressor genes are the regular genes present in the genome which are important for the…

Q: Tissues and differentiation: a) Explain what is meant by determination and differentiation b)…

A: In biology, the process of determination is related to the process in which embryonic stem cells…

Q: Which combination of oncogenes and tumor suppressors is MOST likely to develop a tumor? 1) decreased…

A: Tumor is the characteristic feature of the abnormal cell division. The cell division rate is faster…

Q: The normal copies of tumor-suppressor genes encode proteins that have which three types of…

A: A tumour suppressor gene also known as anti-oncogene is a gene that is responsible to regulate the…

Q: Suppose Nicole recently learned that she inherited a mutant BRCA1 allele from her mother, who had…

A: BRCA1 is a tumor suppressor gene usually expressed in breast cells. It is responsible for repairing…

Q: In some cancer cells, a specific gene has been duplicated many times. Is this gene likely to be an…

A: Cancer is an uncontrolled division of cell that has a defunct apoptosis mechanism. Usually, when…

Q: Mutations in proto-oncogenes that turn them into oncogenes tend to be dominant, while cancer-causing…

A: Tumor suppressor genes are the genes that suppress the formation of tumors in the cells or tissues…

Q: Describe the underlying causes of epigenetic changes associated with cancer.

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: Select the statements that accurately describe different ways that translocations could lead to…

A: Answer-  (A) A translocation breaks up the sequence of a gene for a protein that stimulates…

Q: Which of the following is not a cancer risk factor.

A: Cancer is a disease which is characterized by the abnormal proliferation of living cells. It can…

Q: Many of the mutations in cancer samples are not necessarily driver mutations, but rather passenger…

A: Hematologic childhood cancer can develop in any part of the body, including the blood and lymph…

Q: Which of these events do you think is likely to promote tumorigenesis in affected cells? Group of…

A: Tumorigenesis is the process of forming a tumor, which is an abnormal growth of cells.

Q: Which of the following steps are correct about multistep tumorigenesis (select all that apply)?…

A: When a normal cell undergoes uncontrolled differentiation and division it causes tumor cells. It is…

Q: Which type of mutation would NOT be involved in the inactivation of a tumor suppressor gene?

A: Normal cell growth in body is controlled by -  1. Protooncogene or cellular oncogene - Protooncogene…

Q: Of the following choices a loss of function mutation would most lukely contribute to cancer onset if…

A: Normal DNA contains a particular sequence of DNA. If the sequence of DNA is changed due to external…

Q: Products of proto-oncogenes and tumor-suppressor genes can be     growth factors and growth factor…

A: Normal DNA contains a particular sequence of DNA. If the sequence of DNA is changed due to external…

Q: proto-oncogenes and tumor suppressor genes cause most types of cancer

A: The genes are formed by the Deoxyribonucleic acid (DNA) of an organism. These genes code all of the…

Q: Explain the normal regulation of proto-oncogenes and tumor suppressor genes that prevents cells from…

A: Oncogenes and tumour suppressor genes are two types of genes that relate cell cycle regulation to…

Q: A microarray is a technique used to develop a profile of the messenger RNA being transcribed by…

A: The tumor suppressor genes are the genes that code for a protein whose function is to suppress the…

Q: There are three broad categories of cancer-related genes: proto-oncogenes, tumor suppressor genes,…

A: It is an uncontrollable cell division that get metastasized into surrounding tissues.