The C-myc gene is a proto-oncogene which is highly expressed in breast tissue and appears to cause proliferation of breast tissue and its elevated expression is associated with breast cancer. Based just on the ChIP data from the previous questions (also shown below), which of the three drugs (estrogen, tamoxifen and raloxifene) would you recommend for treating breast cancer? Justify your response and explain the potential side effects of each drug.

Q: Estrogen works by binding to the ER. It includes two types ER alpha and ER beta and the two…

A: Estrogen receptors(ES) are the protein molecules present inside the cell. Their activation takes…

Q: Platelet-derived growth factor (PDGF) is, as its name suggests, stored in and secreted by platelets.…

A: PDGF is naturally synthesized and stored by the body. Its primary role is to encourage the growth…

Q: Refer to the experimental approach (i.e., very briefly describe) and give the results AND…

A: To address this question comprehensively, we need to break down the provided information into its…

Q: When the doctor does blood work on Bob at this point, what blood cells do you expect to be at lower…

A: Red blood cells/ Erythrocytes will be lower than the normal count.

Q: Chromosomal translocations AND mutations in cadherin binding sites can result in cancer. Select one:…

A: Introduction: When a segment of one chromosome separates and joins another chromosome, the process…

Q: Why is it harder to develop a drug that targets a tumor suppressor gene compared to an oncogene…

A: Uncontrolled cell division in the cells may result into the tumor formation. Sometimes the cells may…

Q: manifestations in the event that the BRCA1 tumor suppressor gene accumulates mutations.

A: the cancer cell produces abnormal protein and their uncontrolled growth will lead to formation of…

Q: Herceptin is an antibody that binds to a class of oestrogen receptors and is used to treat some…

A: Introduction: The unregulated proliferation of cells in the breast area is known as breast cancer.…

Q: Carcinogens generate mutations in:   Question 17 options:   anti-oncogenes and tumor activation…

A: Carcinogens are substances or agents that have the potential to cause cancer in living organisms.…

Q: With regard to cancer cells, which of the following are true? DA Cancer cells are clonal, meaning…

A: Ans: Cancer: It is the uncontrolled growth of cells in response to or due to mutation.

Q: Which of the following statements are true about the rate of mutation in tumor cells (select all…

A: Chromosome rearrangements, which occur at high rates due to aneuploidy, an aberrant chromosome…

Q: For many years, targeted therapies for cancer treatment continue to be developed, however more and…

A: Targeted therapy is a type of cancer treatment that uses drugs designed to "target" cancer cells…

Q: Compare and contrast oncogenes and tumor suppressors. Contrast oncogenes and proto-oncogenes.…

A: Genetic changes are the primary cause of cancer, an incredibly complicated and multidimensional…

Q: what category of cancer-related genes is it possible to find inherited variants that are associated…

A: Answer is option 3.

Q: According to the videos and the readings for this unit, what is true of the gut microbiome? The gut…

A: Gut microbiome are the microbiota (range of bacteria, archea and fungi ) that lives inside the gut…

Q: Mrs. Ortez has type III breast cancer and is now concluding the trial portion of a certain research…

A: Stage III breast cancer is a stage where the cancer has spread beyonf the tumor region and might…

Q: Prompts Gain of function. Oncogenes Mutated forms of proto-oncogenes Examples of oncogenes Loss of…

A: cancer is caused by a mutation in genes it is heridatory Generally due to by chance in the genes to…

Q: Answer the following multiple-choice questions about cancer-promoting mutations. A gene whose…

A: Cancer cells by definition, proliferate in defiance of normal controls and are able to invade and…

Q: Using the chromatophore (pigmented) cells of zebra fish as an experimental system, you and a…

A: Cytoplasmic motors Kinesin and dynein both are responsible for long-range transport in many cell…

Q: Why would elevated levels of PSA be suggestive of prostate cancer given what you know about cancer?…

A: The prostate gland is situated below the urinary bladder and is responsible for the production of…

Q: The decision by some high-risk women to have their breasts removed to prevent the possibility of…

A: The type of gene that possesses the potential to cause cancer as a result of mutation is referred to…

Q: Looking at Figure 1, what did Romansik et al. (2007) find regarding the relationship between the…

A: The mitotic index is a measure of the number of cells in a tissue sample that are undergoing cell…

Q: A 6-year old Caucasian girl from northern Europe, with a family history of melanoma, has recently…

A: Melanoma is a kind of cancer affecting the melanocytes (cells that control pigmentation of the…

Q: Mutations in proto-oncogenes that turn them into oncogenes tend to be dominant, while cancer-causing…

A: Tumor suppressor genes are the genes that suppress the formation of tumors in the cells or tissues…

Q: The palladin gene, which plays a role in pancreatic cancer (see theintroduction to this chapter), is…

A: A disease is an abnormal condition that negatively impacts the structure and function of an…

Q: What would be the effect of a mutation that inactivates the p14ARF tumor suppressor upon p53…

A: p53 is known as a cellular tumor antigen 53 is a protein found in vertebrates that is responsible…