Prompts Gain of function. Oncogenes Mutated forms of proto-oncogenes Examples of oncogenes Loss of function. Examples of tumor suppressor genes Tumor suppressor genes Inherited cancer The Knudson's 2-hit hypothesis Both inherited and sporadic cancers. Submitted Answers Choose a match Choose a match Choose a match. Choose a match Choose a match. Choose a match Choose a match Choose a match. Choose a match Choose a match ▼ ▼ ▼ ▼ ▼ ▼ O O is seen in oncogenes, leading to cancer. protect cells from uncontrolled proliferation. O are; CMYC, KRAS & ErBb2 O involve Tumor suppressor genes O requires loss of function in both alleles. are not involved in inherited forms of cancer are oncogenes. is of relevance to inherited cancers. is seen in tumor suppressor genes, leading to cancer. O are; BRCA1, BRCA2 & TP53

Q: 25 of 41 The products of tumor suppressor genes cell division; the products of oncogenes cell…

A: Tumour Suppressor Gene:  A tumour suppressor gene is a type of gene that helps control cell…

Q: 24 of 41 The products of tumor suppressor genes cell division; the products of oncogenes cell…

A: Normal genes that slow cell division, fix DNA errors, or warn cells when to die are known as tumour…

Q: A proto-oncogene is: a gene in the process of evolving into an oncogene     a gene that has…

A: Oncogene is the set of genes that if mutated or triggered due to overexpression can cause cancer. In…

Q: Part 3C: Below is data from a pedigree trace of patients affected with mouse model of pancreatic…

A: Answer  The mode of inheritance shown in the above pedigree is of autosomal recessive

Q: Match the gene name with the gene description. rb BRCA-1 A. tumor suppressor - p53 B. proto-oncogene…

A: Cancer is a condition caused by mutation in the genome that results in infinite cell multiplication…

Q: In tumor cells Rb protein is hyperphosphorylated. In response to that, will p53 level increase or…

A:

Q: What causes cancer (think mutations, repair mechanisms, dna polymerase, symmatic/ germ line, genes +…

A: Cancer can be defined as a disorder in which there is abnormal and uncontrolled proliferation of the…

Q: Put a checkmark next to any of the following scenarios that would make it MORE likely that a cell…

A: Need to find all the options that produce uncontrollable cell division  and to increase chance of…

Q: Translocation of a proto-oncogene to a chromosome region with reduced methylation increases its…

A: Abnormal sequences of DNA methylation, disturbed patterns of histone posttranslational modifications…

Q: Which of the following do cancer cells rely on to be able to divide indefinitely? tumor suppressors…

A: Cancer is defined as the biological disorder in which the cells undergo uncontrolled growth and cell…

Q: Please help me with the genomics/developmental biology question below: Matching A. Proto-oncogenes…

A: The cell cycle is a highly regulated process with different checkpoint ensuring correct events has…

Q: What could you most likely conclude about the drug treatment that produced the following cell cycle…

A: The anticancer drug if its effective then brings cancer cell death

Q: Mutated genes that promote cell proliferation are called:   Question 23 options:…

A: Proto-oncogenes:Proto-oncogenes are normal genes that regulate cell growth, division, and…

Q: T/F : Proto oncogenes and tumor suppressor genes may lead to cancer if mutated multiple times.

A: Proto-oncogenes are normal genes that can become oncogenes when they are mutated in specific ways. A…

Q: Below you will find the normal p53 gene found on chromosome 17 and a mutated version of the gene.…

A: To solve such questions, we should know the corresponding complementarity between the bases and that…

Q: True/False: When first discovered, investigators found it surprising that some single-gene defects…

A: Immunodeficiencies happen when at least one segments of the safe framework is faulty. The most…

Q: The belief that rare mutations within a single cell allow it bypass growth barriers to become…

A: Driver Mutations: These are genetic changes that directly drive growth to cells, allowing them to…

Q: In attempting to design a drug that will impede cell cycle progression in ovarian cancers cells. you…

A: The answer is none of these.The cell cycle is a tightly regulated process that controls the growth…

Q: p53 is an important DNA damage checkpoint protein that stops the transition to S phase and is lost…

A: p53, also known as TP53 or tumor protein (EC :2.7. 1.37) is a gene that codes for a protein that…

Q: Please explain how cancer is a disease of the cell cycle checkpoints. you must explain how the…

A: Cancer is a combined name for various diseases that are caused by a common pathway known as…

Q: Select the statements that accurately describe different ways that translocations could lead to…

A: Answer-  (A) A translocation breaks up the sequence of a gene for a protein that stimulates…

Q: Which one of the following events is unlikely to beassociated with cancer?a. mutation of a cellular…

A: Cancer is basically the uncontrolled proliferation of abnormal or mutated cells in the body. It is…

Q: Select the statements that describe the effect of copy number variation on human phenotypes. An…

A: Copy number variation means the number of deletions or insertions in the human genome which can…

Q: Products of proto-oncogenes and tumor-suppressor genes can be     growth factors and growth factor…

A: Normal DNA contains a particular sequence of DNA. If the sequence of DNA is changed due to external…

Q: S OLIVE ✓ 00:47:29 Labels Ras is an example Can become oncogenes Both copies need to be mutated to…

A: Introduction : Positive growth regulator mutations that lead to hyperactivity are frequently…

Q: There are three broad categories of cancer-related genes: proto-oncogenes, tumor suppressor genes,…

A: It is an uncontrollable cell division that get metastasized into surrounding tissues.

Q: Proto-oncogenes are genes that have the potential to become oncogenes through either mutation or an…

A: Genes are the segments of DNA that code for  proteins. These are passed from parents to offspring. A…

Q: Isothiocyanates are compounds found in vegetables such as broccoli. Such compounds have been shown…

A: The cervix is the lowermost section of the uterus and when a malignant tumour appear here, it’s…

Q: Which of the following could be classified as an oncogene? None are possible oncogenes A mutant of…

A: An oncogene is a mutated form of a proto-oncogene normally present in a cell and is involved in…

Q: The resulting  hypermethylation profiles (of DNA and/or histones) from mutant IDH and high 2-HG…

A: This question appears to be related to the part of hypermethylation profiles within the context of…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.