Below you will find the normal p53 gene found on chromosome 17 and a mutated version of the gene. NORMAL p53 Gene Step 1) Observe the complementary strands of DNA sequence below. ATG ATC GCA AGT AGC GCC GAT AAA TTG CAG TAG TAC TAG CGT TCA TCG CGG СТА TTT AAC GTC ATC Step 2) Using the triplets from the lower strand, transcribe mRNA and write those codons in the boxes below. Step 3) Using the mRNA codons you transcribed above, translate the codons into amino acids to construct the p53 protein. MUTANT p53 Gene Step 4) Observe the complementary strands of DNA sequence below. ATG ATC GCA AGT AGC GCC GAT AAA TTG CAG TAG TAG CGT TCA TCG CGG СТА TTT AAC GTC AGC TAC

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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MUTANT p53 Gene
Step 4) Observe the complementary strands of DNA sequence below.
ATG
АТС
GCA
AGT
AGC
GCC
GAT
AAA
TTG
CAG
TAG
TAC
TAG
CGT
TCA
TCG
CGG
СТА
TTT
AAC
GTC
AGC
Step 5) Using the triplets from the lower strand, transcribe mRNA and write those codons in the boxes below.
Step 6) Using the mRNA codons you transcribed above, translate the codons into amino acids to construct the
p53 protein.
ANALYSIS
1. Circle/Highlight all changes in the DNA and resulting MRNA and amino acids that occurred because of
the mutation.
Transcribed Image Text:MUTANT p53 Gene Step 4) Observe the complementary strands of DNA sequence below. ATG АТС GCA AGT AGC GCC GAT AAA TTG CAG TAG TAC TAG CGT TCA TCG CGG СТА TTT AAC GTC AGC Step 5) Using the triplets from the lower strand, transcribe mRNA and write those codons in the boxes below. Step 6) Using the mRNA codons you transcribed above, translate the codons into amino acids to construct the p53 protein. ANALYSIS 1. Circle/Highlight all changes in the DNA and resulting MRNA and amino acids that occurred because of the mutation.
Below you will find the normal p53 gene found on chromosome 17 and a mutated version of the gene.
NORMAL p53 Gene
Step 1) Observe the complementary strands of DNA sequence below.
ATG
АТС
GCA
AGT
AGC
GCC
GAT
AAA
TTG
CAG
TAG
TAC
TAG
CGT
TCA
TCG
CGG
СТА
TTT
AAC
GTC
АТС
Step 2) Using the triplets from the lower strand, transcribe MRNA and write those codons in the boxes below.
Step 3) Using the mRNA codons you transcribed above, translate the codons into amino acids to construct the
p53 protein.
MUTANT p53 Gene
Step 4) Observe the complementary strands of DNA sequence below.
ATG
ATC
GCA
AGT
AGC
GCC
GAT
AAA
TTG
CAG
TAG
TAG
CGT
TCA
TCG
CGG
СТА
TTT
AAC
GTC
AGC
TAC
Transcribed Image Text:Below you will find the normal p53 gene found on chromosome 17 and a mutated version of the gene. NORMAL p53 Gene Step 1) Observe the complementary strands of DNA sequence below. ATG АТС GCA AGT AGC GCC GAT AAA TTG CAG TAG TAC TAG CGT TCA TCG CGG СТА TTT AAC GTC АТС Step 2) Using the triplets from the lower strand, transcribe MRNA and write those codons in the boxes below. Step 3) Using the mRNA codons you transcribed above, translate the codons into amino acids to construct the p53 protein. MUTANT p53 Gene Step 4) Observe the complementary strands of DNA sequence below. ATG ATC GCA AGT AGC GCC GAT AAA TTG CAG TAG TAG CGT TCA TCG CGG СТА TTT AAC GTC AGC TAC
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