Select the statements that describe the effect of copy number variation on human phenotypes. An increase in copy number can cause gene function loss due to chromosome breaks. A decrease in copy number can cause Mendelian autosomal disorders due to point mutations. Oncogene overexpression due to a gain in copy number can cause cancer. Increase in the copy number of immunity genes can result in increased pathogen resistance. Copy number variations are associated with polygenic disorders such as schizophrenia.
Select the statements that describe the effect of copy number variation on human phenotypes. An increase in copy number can cause gene function loss due to chromosome breaks. A decrease in copy number can cause Mendelian autosomal disorders due to point mutations. Oncogene overexpression due to a gain in copy number can cause cancer. Increase in the copy number of immunity genes can result in increased pathogen resistance. Copy number variations are associated with polygenic disorders such as schizophrenia.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:Select the statements that describe the effect of copy number variation on human phenotypes.
An increase in copy number can cause gene function loss due to chromosome breaks.
A decrease in copy number can cause Mendelian autosomal disorders due to point mutations.
Oncogene overexpression due to a gain in copy number can cause cancer.
Increase in the copy number of immunity genes can result in increased pathogen resistance.
Copy number variations are associated with polygenic disorders such as schizophrenia.
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