A defective gene on chromosome 15 causes Tay-Sachs disease. It is a central nervous system neurodegenerative disease that most often affects infants, though older children and adults can have late-onset forms of the disease. The defective gene prevents the body from making a protein called hexosaminidase A. Without, hexosaminidase A, chemicals called gangliosides build up in the nerve cells of the brain, destroying brain cells. If individuals II-1 and II-2 have another child, what is the probability they will have a child affected by Tay-Sachs? Select one: a. 0.00 b. 0.25 c. 0.50 d. 1.00

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A: During transcription, the DNA double helix unwinds and the RNA polymerase enzyme reads the template…

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A: Answer  The mode of inheritance shown in the above pedigree is of autosomal recessive

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A: ADA means Adenosine deaminase deficiency and SCID is severe combined immunodeficiency.  ADA-SCID is…

Q: i. Mutant A has a single base pair substitution with the T/A being replaced with C/G base pair at…

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Q: What phase of mitosis is pictured? O prophase O prometaphase O metaphase O anaphase O telophase

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A: Heterozygous  A condition where two different variety of a same allele present on different locus of…

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A: A negative, or deleterious, mutation reduces the organism's fitness. A beneficial or advantageous…

Q: C. Two mutations are known in the population, one shaded in yellow and one in blue, in the TEMPLATE…

A:

Q: what category of cancer-related genes is it possible to find inherited variants that are associated…

A: Answer is option 3.

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Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.