3.Tay Sachs is a lysosomal storage disease that is inherited in an autosomal recessive manner (T= dominant allele; t = recessive allele). Individuals with Tay Sachs have a defect in the gene encoding hexosaminidase A, a lysosomal enzyme that breaks down cell membrane components called gangliosides. The inability to break down gangliosides causes harmful quantities of this lipid to accumulate in nerve cells of the brain, eventually leading to premature death of affected cells. There is no known cure for the disease, and death usually occurs by age 4. Jack and Jill have a child who has Tay-Sachs. What do you know about the genotypes of Jack and Jill? A.has the genotype DD B.has the genotype Dd C.is still of unknown genotype since there were offspring of both deaf and hearing phenotypes. D.has the genotype dd

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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3.Tay Sachs is a lysosomal storage disease that is inherited in an autosomal recessive manner (T= dominant allele; t = recessive allele). Individuals with Tay Sachs have a defect in the gene encoding hexosaminidase A, a lysosomal enzyme that breaks down cell membrane components called gangliosides. The inability to break down gangliosides causes harmful quantities of this lipid to accumulate in nerve cells of the brain, eventually leading to premature death of affected cells. There is no known cure for the disease, and death usually occurs by age 4. Jack and Jill have a child who has Tay-Sachs. What do you know about the genotypes of Jack and Jill? A.has the genotype DD B.has the genotype Dd C.is still of unknown genotype since there were offspring of both deaf and hearing phenotypes. D.has the genotype dd
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