4. Compare the DNA sequences of individuals with Alzheimer's disease and their family members. Two codons in the APP gene sequence are different in the two patients with Alzheimer's disease compared to individuals without the disease. Consider the first codon that's different and complete the table below. Codon in Codon in Amino Acid DNA template strand MRNA APP gene in individuals without Alzheimer's disease APP gene in individuals with Alzheimer's disease Does the change in this codon represent a silent or a missense mutation? Explain.
4. Compare the DNA sequences of individuals with Alzheimer's disease and their family members. Two codons in the APP gene sequence are different in the two patients with Alzheimer's disease compared to individuals without the disease. Consider the first codon that's different and complete the table below. Codon in Codon in Amino Acid DNA template strand MRNA APP gene in individuals without Alzheimer's disease APP gene in individuals with Alzheimer's disease Does the change in this codon represent a silent or a missense mutation? Explain.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:4. Compare the DNA sequences of individuals with Alzheimer's disease and their family members. Two codons
in the APP gene sequence are different in the two patients with Alzheimer's disease compared to individuals
without the disease. Consider the first codon that's different and complete the table below.
Codon in
Codon in
Amino Acid
DNA template strand
MRNA
APP gene in individuals
without Alzheimer's
disease
APP gene in individuals
with Alzheimer's disease
Does the change in this codon represent a silent or a missense mutation? Explain.
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