1. Transcribe and translate the mutated DNA sequences, CIRCLE the mutation, and classify each type of mutation as either Deletion, Insertion, or Substitution AND the effects of the mutation as either frameshift, missense, silent or nonsense. ۷۷۷۷ Original Sequence: mRNA sequence: Amino Acid Sequence: Mutated Sequence #1: mRNA Sequence: Amino Acid Sequence: futationi TACAC CT T G G C G A C G ACT AUGUGGA ACCG CUG CUGA MET-TRP – ASN – ARG - CYS - STOP TACATC TTG G ACGAC T

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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1. Transcribe and translate the mutated DNA sequences, CIRCLE the mutation, and classify each type of
mutation as either Deletion, Insertion, or Substitution AND the effects of the mutation as either
frameshift, missense, silent or nonsense. ۷۷۷۷
Original Sequence:
mRNA sequence:
Amino Acid Sequence: MET-TRP – ASN - ARG - CYS - STOP
Mutated Sequence #1:
mRNA Sequence:
Amino Acid Sequence:
Type of Mutation:
Mutation Effect:
Mutated Sequence #2:
mRNA Sequence:
Amino Acid Sequence:
Type of Mutation:
Mutation Effect:
TACAC CTT G G C G A CG ACT
AUGUG GAA C C G C UG CUGA
TACAT CTTG G C G A C G ACT
TAC GAC CTT G G C G A CG ACT
First base of codon
C
A
UUU
UUC
UUA
UUG
CUU
CUC
CUA
CUG
U
AUU
AUC
>Phe
Leu
>Leu
ACU
ACC
AUA
ACA
AUG Met ACG
GUU
GCU
GUC
GCC
GUA
GCA
GUG
GCG
lle
Second base of codon
C
A
- Val
UCU
UCC
UCA
UCG
CCU
CCC
CCA
CCG
>Ser
>Pro
Thr
Ala
UAU
UAC
UAA
UAG
CAU
CAC
CAA
CAG
AAU
AAC
AAA
Lys
AAG LYS
GAU
GAC Asp
GAA
>Glu
GAG
З туг
>His
G
UGA
UGG
CGU
CGC
CGA
CGG
AGU
Asn AGC-
AGA
AGG.
GGU
GGC
GGA
GGG
Gin
UGU
UGCC
U
C
A
Trp G
U
>Arg
>Ser
>Arg
Gly
C
A
G
U
C
A
G
U
C
A
G
Third base of codon
Transcribed Image Text:1. Transcribe and translate the mutated DNA sequences, CIRCLE the mutation, and classify each type of mutation as either Deletion, Insertion, or Substitution AND the effects of the mutation as either frameshift, missense, silent or nonsense. ۷۷۷۷ Original Sequence: mRNA sequence: Amino Acid Sequence: MET-TRP – ASN - ARG - CYS - STOP Mutated Sequence #1: mRNA Sequence: Amino Acid Sequence: Type of Mutation: Mutation Effect: Mutated Sequence #2: mRNA Sequence: Amino Acid Sequence: Type of Mutation: Mutation Effect: TACAC CTT G G C G A CG ACT AUGUG GAA C C G C UG CUGA TACAT CTTG G C G A C G ACT TAC GAC CTT G G C G A CG ACT First base of codon C A UUU UUC UUA UUG CUU CUC CUA CUG U AUU AUC >Phe Leu >Leu ACU ACC AUA ACA AUG Met ACG GUU GCU GUC GCC GUA GCA GUG GCG lle Second base of codon C A - Val UCU UCC UCA UCG CCU CCC CCA CCG >Ser >Pro Thr Ala UAU UAC UAA UAG CAU CAC CAA CAG AAU AAC AAA Lys AAG LYS GAU GAC Asp GAA >Glu GAG З туг >His G UGA UGG CGU CGC CGA CGG AGU Asn AGC- AGA AGG. GGU GGC GGA GGG Gin UGU UGCC U C A Trp G U >Arg >Ser >Arg Gly C A G U C A G U C A G Third base of codon
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