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G-LO37 Identify the consequences of mutations in different regions of a gene. The image below represents two strands of DNA: the top one corresponds to a healthy individual, and the bottom one of a sibling potentially affected with a disease due to genetic mutations Mutation 1 First letter A U C A G U UUU UUC Phe UUG} Leu CUU CUC CUA CUG Leu AUU AUC lle AUA AUG Met GUU GUC GUA GUG Val Mutation 2 500 AGG 500 GGG Second letter C UCU UCC UCA UCG CCU CCC CCA CCG ACU ACC ACA ACG GCU GCC GCA GCG Ser - Pro Thr Ala A Mutation 4 1235 ATT 1236 CAU CAC J His CAG} Gin The change in amino acid will be from ILE to PHE Tyr TTT The change will be from a STOP codon to LYS GACAsp GAG Glu Select all that applies about Mutation 4 (position +1235, EXON): Mutation 3 UAU UGU UAC T UGC Cys UAA Stop UGA Stop A UAG Stop UGG Trp CGU CGC CGA CGG It will produce a protein with a different amino acid for this codon G GGU GGC GGA GGG Ser AACAsn AGC Se AAGLYS AGA Arg 1536 It will produce a protein that is longer than in the healthy individual G 1536 C Arg Exons are spliced out in immature mRNA so the mutation will have no effect Gly Healthy 6 Individual 5 Affected brother 040כ 040כ 040כ 040כ G Third letter

G-LO37 Identify the consequences of mutations in different regions of a gene. The image below represents two strands of DNA: the top one corresponds to a healthy individual, and the bottom one of a sibling potentially affected with a disease due to genetic mutations Mutation 1 First letter A U C A G U UUU UUC Phe UUG} Leu CUU CUC CUA CUG Leu AUU AUC lle AUA AUG Met GUU GUC GUA GUG Val Mutation 2 500 AGG 500 GGG Second letter C UCU UCC UCA UCG CCU CCC CCA CCG ACU ACC ACA ACG GCU GCC GCA GCG Ser - Pro Thr Ala A Mutation 4 1235 ATT 1236 CAU CAC J His CAG} Gin The change in amino acid will be from ILE to PHE Tyr TTT The change will be from a STOP codon to LYS GACAsp GAG Glu Select all that applies about Mutation 4 (position +1235, EXON): Mutation 3 UAU UGU UAC T UGC Cys UAA Stop UGA Stop A UAG Stop UGG Trp CGU CGC CGA CGG It will produce a protein with a different amino acid for this codon G GGU GGC GGA GGG Ser AACAsn AGC Se AAGLYS AGA Arg 1536 It will produce a protein that is longer than in the healthy individual G 1536 C Arg Exons are spliced out in immature mRNA so the mutation will have no effect Gly Healthy 6 Individual 5 Affected brother 040כ 040כ 040כ 040כ G Third letter

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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G-LO37 Identify the consequences of mutations in different regions of a gene. The image below represents two strands of DNA: the top one corresponds to a healthy individual, and the bottom one of a sibling potentially affected with a disease due to genetic mutations Mutation 1 First letter A U C A U UUC UUGL CUU CUC CUA CUG Phe GUU GUC GUA GUG Leu Leu AUU AUC lle AUA AUG Met Val Mutation 2 500 AGG 500 GGG C Second letter UCU UCC UCA UCG CCU CCC CCA CCG ACU ACC ACA ACG GCU GCC GCA GCG Ser Pro Thr Ala Mutation 4 1235 ATT 1235 The change in amino acid will be from ILE to PHE + TTT CAC His CAA Gin CAGJ AAU Asn The change will be from a STOP codon to LYS UAC Tyr UGC Cys UAA Stop UGA Stop UAG Stop UGG Trp Select all that applies about Mutation 4 (position +1235, EXON): Mutation 3 1535 CGU CGC CGA CGG AAGLys GAUJASP GGU GAC Glu GGA GGC GAGJ GGG It will produce a protein with a different amino acid for this codon G G It will produce a protein that is longer than in the healthy individual 1535 AGC Ser AGA AGG Arg C Arg Exons are spliced out in immature mRNA so the mutation will have no effect Gly Healthy 5 Individual 5 Affected brother DUA DUA DUA ULAG Third letter
Transcribed Image Text:G-LO37 Identify the consequences of mutations in different regions of a gene. The image below represents two strands of DNA: the top one corresponds to a healthy individual, and the bottom one of a sibling potentially affected with a disease due to genetic mutations Mutation 1 First letter A U C A U UUC UUGL CUU CUC CUA CUG Phe GUU GUC GUA GUG Leu Leu AUU AUC lle AUA AUG Met Val Mutation 2 500 AGG 500 GGG C Second letter UCU UCC UCA UCG CCU CCC CCA CCG ACU ACC ACA ACG GCU GCC GCA GCG Ser Pro Thr Ala Mutation 4 1235 ATT 1235 The change in amino acid will be from ILE to PHE + TTT CAC His CAA Gin CAGJ AAU Asn The change will be from a STOP codon to LYS UAC Tyr UGC Cys UAA Stop UGA Stop UAG Stop UGG Trp Select all that applies about Mutation 4 (position +1235, EXON): Mutation 3 1535 CGU CGC CGA CGG AAGLys GAUJASP GGU GAC Glu GGA GGC GAGJ GGG It will produce a protein with a different amino acid for this codon G G It will produce a protein that is longer than in the healthy individual 1535 AGC Ser AGA AGG Arg C Arg Exons are spliced out in immature mRNA so the mutation will have no effect Gly Healthy 5 Individual 5 Affected brother DUA DUA DUA ULAG Third letter
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