12. The following codons and the amino acids they encode is as follows: AUG = Met %3D UUU, UUC = Phe UUA, UUG = Leu UCU, UCC = Ser CCU, CCC = Pro ACU, ACC = Thr %3D %3D %3D %3D The 5' - ACU-UUC-ACU-AUG-UUU-UUA-UCC-UCC-ACU-CCU-UGA-3' MRNA transcript results in a polypeptide. (a) Give the sequence of amino acids in the primary structure of the polypeptide. (3) (b) Give the sequence of nucleotides corresponding to this transcript in: (i) the DNA strand that was read to produce the MRNA (5) (ii) the DNA strand that was NOT read (the coding strand) (5) (c) How many distinct aminoacyl-tRNA synthetases would be used in the synthesis of this polypeptide? (1) (d) Name TWO characteristics of the genetic code that are evident in the data given in the question. (2)
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
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