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D A mutation in the Pitx1 gene prevents normal hindlimb formation in mouse embryos. Analyses of the presence and length of the gene, its mRNA transcript, and the protein produced show the following results: DNA sequence: normal length mRNA: present, normal length protein: present, shorter than normal Which of the following is the most likely explanation for the mutation? Selected answer will be automatically saved. For keyboard navigation, press up/down arrow keys to select an answer. The mutation removes a transcription factor binding site in a cis-regulatory region of Pitx1. a с It is a nonsense mutation in the Pitx1 coding region that changes a codon for an amino acid into a stop codon. It is a missense mutation in the Pitx1 coding region that changes a single amino acid. d It is a mutation in an enhancer that prevents a transcription factor from binding.

D A mutation in the Pitx1 gene prevents normal hindlimb formation in mouse embryos. Analyses of the presence and length of the gene, its mRNA transcript, and the protein produced show the following results: DNA sequence: normal length mRNA: present, normal length protein: present, shorter than normal Which of the following is the most likely explanation for the mutation? Selected answer will be automatically saved. For keyboard navigation, press up/down arrow keys to select an answer. The mutation removes a transcription factor binding site in a cis-regulatory region of Pitx1. a с It is a nonsense mutation in the Pitx1 coding region that changes a codon for an amino acid into a stop codon. It is a missense mutation in the Pitx1 coding region that changes a single amino acid. d It is a mutation in an enhancer that prevents a transcription factor from binding.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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口 A mutation in the Pitx1 gene prevents normal hindlimb formation in mouse embryos. Analyses of the presence and length of the gene, its mRNA transcript, and the protein produced show the following results: DNA sequence: normal length mRNA: present, normal length protein: present, shorter than normal Which of the following is the most likely explanation for the mutation? Selected answer will be automatically saved. For keyboard navigation, press up/down arrow keys to select an answer. d a The mutation removes a transcription factor binding site in a cis-regulatory region of Pitx1. с It is a nonsense mutation in the Pitx1 coding region that changes a codon for an amino acid into a stop codon. It is a missense mutation in the Pitx1 coding region that changes a single amino acid. It is a mutation in an enhancer that prevents a transcription factor from binding.
Transcribed Image Text:口 A mutation in the Pitx1 gene prevents normal hindlimb formation in mouse embryos. Analyses of the presence and length of the gene, its mRNA transcript, and the protein produced show the following results: DNA sequence: normal length mRNA: present, normal length protein: present, shorter than normal Which of the following is the most likely explanation for the mutation? Selected answer will be automatically saved. For keyboard navigation, press up/down arrow keys to select an answer. d a The mutation removes a transcription factor binding site in a cis-regulatory region of Pitx1. с It is a nonsense mutation in the Pitx1 coding region that changes a codon for an amino acid into a stop codon. It is a missense mutation in the Pitx1 coding region that changes a single amino acid. It is a mutation in an enhancer that prevents a transcription factor from binding.
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