Which of the following statements best describes the differences in the regulation of cardiac and skeletal muscle contraction? The amount of contractile force actively generated by muscle cells is increased by stretch in skeletal muscle and decreased by stretch in cardiac muscle. Cardiac muscle is stimulated by motor neurons and skeletal muscle by neurones from the autonomic nervous system. Skeletal muscle contractile force is augmented by increasing the firing frequency of action potentials whereas cardiac muscle contractile force is enhanced by noradrenaline increasing calcium influx through ion channels. Ryanodine receptors in skeletal muscle are opened by a mechanism that requires calcium influx whereas in cardiac muscle membrane depolarisation alone without calcium influx is sufficient to open ryanodine receptors.
Which of the following statements best describes the differences in the regulation of cardiac and skeletal muscle contraction?
The amount of contractile force actively generated by muscle cells is increased by stretch in skeletal muscle and decreased by stretch in cardiac muscle. |
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Cardiac muscle is stimulated by motor neurons and skeletal muscle by neurones from the autonomic nervous system. |
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Skeletal muscle contractile force is augmented by increasing the firing frequency of action potentials whereas cardiac muscle contractile force is enhanced by noradrenaline increasing calcium influx through ion channels. |
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Ryanodine receptors in skeletal muscle are opened by a mechanism that requires calcium influx whereas in cardiac muscle membrane depolarisation alone without calcium influx is sufficient to open ryanodine receptors. |
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