Question in photo 7. Consider p53. The p53 gene codes for a protein(single circle below). Protein monomers formdimers (two circles attached). Two dimers cometogether to form the functional p53. This triggersother pathways that can result in either repair ofthe damage, or cell death. In this way, p53 issometime called the "guardian of the genome"because the function of p53 reduces mutation. Ifdamage is not detected, it can lead to anincrease in the frequency of mutation, which canhave negative impacts such as increased cancerrisk. The reason for this is that, over time, ifmutations occur that result in more, unregulatedcell division, that is a cancerous phenotype.In a heterozygote (+/m)Wild typeDimersMutantNot functionalFunçtjonalBelow we are comparing two alleles: wildtype(functional) and mutant (not functional). Normally,p53 can bind to DNA and detect damage. Herewe are considering a heterozygote: one wildtype allele, one mutant allele.DNADNAConsider two phenotypes:1. Binding to DNA2. Cancer risk.For each phenotype level, would the wildtype or mutant allele be considered dominant (oris neither allele dominant)? Explain.

Heterozygous A condition where two different variety of a same allele present on different locus of…

Below we are comparing two alleles: wildtype (functional) and mutant (not functional). Normally, p53 can bind to DNA and detect damage. Here we are considering a heterozygote: one wildtype allele, one mutant allele. DNA DNA Consider two phenotypes: 1. Binding to DNA 2. Cancer risk. For each phenotype level, would the wildtype or mutant allele be considered dominant (or is neither allele dominant)? Explain.