Severe combined immunodeficiency disease is a life-threatening genetic disease in which children are born with defective B-cell and Tcell function. These children are susceptible to severe infections, such as pneumonia, meningitis, or blood-borne infections. They can also be infected and sickened by live viruses that are present in some vaccines. Children with some forms of severe combined immunodeficiency disease have mutations in their RAG1 or RAG2 genes. Provide a possible explanation for how mutations in these genes might lead to the symptoms of this disorder
Severe combined immunodeficiency disease is a life-threatening genetic disease in which children are born with defective B-cell and Tcell function. These children are susceptible to severe infections, such as pneumonia, meningitis, or blood-borne infections. They can also be infected and sickened by live viruses that are present in some vaccines. Children with some forms of severe combined immunodeficiency disease have mutations in their RAG1 or RAG2 genes. Provide a possible explanation for how mutations in these genes might lead to the symptoms of this disorder
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Severe combined immunodeficiency disease is a life-threatening
genetic disease in which children are born with defective B-cell and Tcell
function. These children are susceptible to severe infections, such
as pneumonia, meningitis, or blood-borne infections. They can also be
infected and sickened by live viruses that are present in some
vaccines. Children with some forms of severe combined
immunodeficiency disease have mutations in their RAG1 or RAG2
genes. Provide a possible explanation for how mutations in these
genes might lead to the symptoms of this disorder
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