The following interactions occur during the expression and secretion of an antibodyheavy-chain protein. Number them in the order that each takes place for the firsttime.A spliceosome interacts with the 5th intron (but not with the 6th).A B cell-specific protein bound to an enhancer interacts with a proteincomplex bound to the promoter.A signal recognition particle (SRP) interacts with a signal peptidesequence.A recombinase acts on copies of a specific DNA sequence in the gene.

1. A signal peptide sequence and a signal recognition particle (SRP) interact (Step c): - Early in…

Answered: The following interactions occur during…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Similar questions

A haploid E. coli cell has the genotype I ¯ P+ O+ Z+ Y ¯ where the I ¯ indicates that the repressor protein cannot bind to the operator due to a mutation. Which of the following statements about cells with this lac operon genotype are correct? I ¯ P+ O+ Z+ Y ¯ Select all that apply. β-galactosidase will be transcribed constitutively. The cells are able to import lactose across the cell membrane. The cells are lac+ and are able to grow on a medium with lactose but no glucose. RNA polymerase can bind to the promoter.
Drug X shown below is a kinase inhibitor used to treat multiple types of breast cancer. Breast cancer cells are treated with the drug and after 8 hr are lysed and the presence of various proteins is shown by a band on a western blot. The presence of the phosphorylated form of the protein is shown by the presence of a band when probed with antibodies that recognize the phosphorylated form of protein and are indicated by a p- in front of protein name (e.g. p-AKT). Based on this information, which kinase is likely the target and is inhibited by Justify your answer in 3-4 sentences. Drug X. F FF N. -N S IZ H₂N `N No Drug (+) Drug p-AKT AKT p-GSK3B GSK3B p-p70S6K p70S6K
You are a pediatric specialty nurse caring for a patient infected with the mumps virus. The virus has infected the parotid salivary glands producing acute illness. Which of the following apply during the early, symptomatic stages of illness: O The patient has previously been vaccinated against the mumps virus O The patient has a population of mumps-specific memory cells O The patient has a high level of mumps-specific IgE O The patient has a small number of mumps-specific TH, Tc, and B cells O The patient has no mumps-specific TH, Tc, and B cells
You plan to synthesize a peptide to be used as a vaccine to treat melanoma, a particularly aggressive form of skin cancer. Normally, gp100, a protein on the surface of melanocytes, activates cell growth when it is bound by its ligand. Activation of the growth pathway depends on the presence of threonine in the ligand. The effective peptide vaccine will mimic the natural ligand, but won’t cause cell growth and division. Below is the sequence of the natural ligand: LDMKTAG In order to ensure your newly designed peptide vaccine does not cause cell growth upon binding, you must substitute the Threonine residue at position 5. What amino acid would you replace it with, bearing in mind that the peptide should still be similar enough to bind to the gp100 protein in the surface of melanocytes. Explain your choice. Your vaccine will be administered as a topical cream, and you require your peptide to have an overall neutral charge in order to be functional. At what pH should you formulate…
How does a T-cell recognize a cell infected by a virus? Select one: a. binding of viral DNA in an infected cell. b. binding of viral peptide in the cytosol of infected cell c. binding of viral mRNA in the cytosol of the infected cell d. binding of viral peptide on the surface of the infected cell e. binding of viral mRNA on the surface of the infected cell
Retroviruses may transform cells in more than one way. From the figure given below, explain the two ways by which cells are transformed. You have the purified protein overexpressed in the cell. How will you determine which pathway of expression is occurring in the cell? Promoter V-onc Retroviral DNA - Retroviral DNA Retroviral Proto- promoter oncogene Proto- V-onc oncogene Host cell DNA - Host cell DNA Excessive Lexpression Expression C-onc V-onc MRNA W MRNA Abnormal protein (hyperactive) Protein product Abnormal cell growth
How can we easily determine VEGF expression in a western blot experiment? By using fluorescent microscopy to view its transport into the cell By using a primary antibody targeting VEGF By adding purified VEGFR to an SDS polyacrylamide gel By doing a mass spectrometry analysis
The production of antibodies is an example of regulation of gene expression at which level? Translational Level Genomic Level Transciptional Level Post-Transcriptional Level
In the tryptophan operon, tryptophan is considered a Group of answer choices coactivator inducer an enhancer corepressor an attenuator

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