Human immunodeficiency virus (HIV), the causative agent of acquired immune deficiency syndrome (AIDS) infects T-helper cells that have the CD4 receptor on their surface: gp120 CD4 receptor CXCR4 coreceptor RNA- -Reverse transcriptase erzyme Core with protein coat Capsomeres of protein cont Envelope Toel DNA (b) HIV infecting a T coll with CD4 receptors. and CXCRA coroceptors which are distributod (a) Structure of HIV over the surface of the cell Copyright 2001 Benjamin Cummings an imprint ot Addson Wesley Longman, Inc. A As shown in the above diagram, HIV attaches to a susceptible cell by a binding interaction between the gp120 protein on the virus protein and the CD4 and CXCR4 receptors on the surface of the T-helper cell. What will be the next event in the virus life cycle? B. One mechanism for transmission of HIV is direct contact during sexual activity. What is the other common mechanism of transmission?

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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Human immunodeficiency virus (HIV), the causative agent of acquired immune deficiency syndrome (AIDS) infects T-helper cells that have the CD4 receptor on their surface:
gp120
CD4 receptor
-CXCR4 coreceptor
RNA-
Revorse
transcriptase
enzyme
Core with -
protein coat
Capsomeres of
protein coat
Envelope
T cll
DNA
(a) Structure of HIV
(b) HIV infecting a T cell with CD4 receptors,
and CXCR4 coreceptors which are distributed
over the surface of the cell
Copyright e 2001 Benjamin Cummings, an imprint of Addison Wesloy Longman, Inc.
A. As shown in the above diagram, HIV attaches to a susceptible cell by a binding interaction between the gp120 protein on the virus protein and the CD4 and CXCR4 receptors on the surface of the T-helper cell. What will be the next event in the virus life cycle?
B. One mechanism for transmission of HIV is direct contact during sexual activity. What is the other common mechanism of transmission?
Transcribed Image Text:Human immunodeficiency virus (HIV), the causative agent of acquired immune deficiency syndrome (AIDS) infects T-helper cells that have the CD4 receptor on their surface: gp120 CD4 receptor -CXCR4 coreceptor RNA- Revorse transcriptase enzyme Core with - protein coat Capsomeres of protein coat Envelope T cll DNA (a) Structure of HIV (b) HIV infecting a T cell with CD4 receptors, and CXCR4 coreceptors which are distributed over the surface of the cell Copyright e 2001 Benjamin Cummings, an imprint of Addison Wesloy Longman, Inc. A. As shown in the above diagram, HIV attaches to a susceptible cell by a binding interaction between the gp120 protein on the virus protein and the CD4 and CXCR4 receptors on the surface of the T-helper cell. What will be the next event in the virus life cycle? B. One mechanism for transmission of HIV is direct contact during sexual activity. What is the other common mechanism of transmission?
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