Classify the events as possible precursors for a professional antigen presenting cell (pAPC) activating Signal 1, Signal 2, or Signal 3 in an interaction with a naïve CD4+ T cell. Not all of the events will be used. Signal 1 MHC restriction endogenous pathway of antigen presentation V(D)J recombination lineage commitment Signal 2 Signal 3 exogenous pathway of antigen presentation PRR signaling in pAPC activates CD80 expression PRR signaling in pAPC activates IL-2 expression Answer Bank IL-2α chain gene expression

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Classify the events as possible precursors for a professional antigen presenting cell (pAPC) activating Signal 1, Signal 2, or
Signal 3 in an interaction with a naïve CD4+ T cell. Not all of the events will be used.
Signal 1
MHC restriction
endogenous pathway of antigen presentation
V(D)J recombination
lineage commitment
Signal 2
Signal 3
exogenous pathway of antigen presentation
PRR signaling in pAPC activates CD80
expression
PRR signaling in pAPC activates IL-2
expression
Answer Bank
IL-2α chain gene expression
Transcribed Image Text:Classify the events as possible precursors for a professional antigen presenting cell (pAPC) activating Signal 1, Signal 2, or Signal 3 in an interaction with a naïve CD4+ T cell. Not all of the events will be used. Signal 1 MHC restriction endogenous pathway of antigen presentation V(D)J recombination lineage commitment Signal 2 Signal 3 exogenous pathway of antigen presentation PRR signaling in pAPC activates CD80 expression PRR signaling in pAPC activates IL-2 expression Answer Bank IL-2α chain gene expression
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