Consider the V region domains of the TCRα and TCRβ chains and the genetic loci that encode them. Which TCR chain is more genetically analogous to Ig light chain and Why?
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
Consider the V region domains of the TCRα and TCRβ chains and the genetic loci that encode them.
Which TCR chain is more genetically analogous to Ig light chain and Why?
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