If a particular proto-oncogene has been altered by mutation into an oncogene such that it is contributing to a cancer phenotype, which of the following must be TRUE?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Please answer question 8

If a particular proto-oncogene has been altered by mutation into an
oncogene such that it is contributing to a cancer phenotype, which of
the following must be TRUE?
One copy
the
gene must have gain-of-function mutations in any cell
Both copies the gene must have loss-of-function mutations in the same cell
More than one of the listed options is possible
One
сорy
the
gene must have loss-of-function mutations in a cell
Both copies the gene must be hypermethylated in the same cell
Transcribed Image Text:If a particular proto-oncogene has been altered by mutation into an oncogene such that it is contributing to a cancer phenotype, which of the following must be TRUE? One copy the gene must have gain-of-function mutations in any cell Both copies the gene must have loss-of-function mutations in the same cell More than one of the listed options is possible One сорy the gene must have loss-of-function mutations in a cell Both copies the gene must be hypermethylated in the same cell
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