Compare and contrast the genetic defects that can lead to disruption of a tumor suppressor gene compared to the mechanisms for activatio

Q: The Bcl-2 protein was initially discovered via its ability to contribute to progression of B-cells…

A: Cancer is a disease caused by abnormal cell division.

Q: Compare and contrast oncogenes and tumor suppressors. Contrast oncogenes and proto-oncogenes.…

A: Genetic changes are the primary cause of cancer, an incredibly complicated and multidimensional…

Q: Which genetic cancer predisposition syndrome is caused by germ-line mutations in the p53 gene and is…

A: P53 is the tumor suppressor protein (TP53 in humans) which is also described as the guardian of the…

Q: The TP53 gene provides instructions for making a protein called tumor protein p53. Known as the…

A: Deoxyribonucleic acid, abbreviated as DNA, is a double-helix made-up of nucleic acids. Its role in…

Q: Explain why metastasis can lead to multiplesecondary tumors in different sites.

A: When there is some mutation that occurs in the DNA of any cell that leads to abnormal and…

Q: "In the cellular regulatory pathways that control cell growth and proliferation, the products of…

A: Normal genes that are changed to become oncogenes are known as proto-oncogenes. They carry out a…

Q: Describe, using specific examples, the differences in how a growth factor gene and a tumor…

A: When we talk about cancer, there are certain genes associated with it. Oncogenes are genes that are…

Q: Explain why p53 is mutated in the vast majority of human cancers.

A: Any isoform of a protein encoded by homologous genes in multiple animals, such as TP53 and Trp53, is…

Q: The best strategy for treating a specific type of human tumor can depend on identifying the type of…

A: Part A. IFS are the ones that provide abundant buffering system in order to protect against…

Q: Explain in detail two different genetic mutations that can promote the development of cancer.…

A: A mutation in a gene that codes for a protein involved in a crucial biological process, such as DNA…

Q: ''In the cellular regulatory pathways that controlcell growth and proliferation, the products of…

A: Cell regulation involves a complex mechanism of different cell signaling pathways that work in a…

Q: Explain the difference between proto-oncogene and tumor suppressor mutations in terms of its…

A: Cancer is a medical condition that is characterized by the growth of tumors in the body of an…

Q: proto-oncogenes and tumor suppressor genes cause most types of cancer

A: The genes are formed by the Deoxyribonucleic acid (DNA) of an organism. These genes code all of the…

Q: Explain the following figure. According to this model, what are the two major phases of metastasis…

A: The figures tells about the metastasis. Metastasis is the spread of cancer cells to the healthy or…

Q: Prompts Šubmitted Answers protect cells from uncontrolled proliferation Gain of function Choose a…

A: Introduction: Sporadic cancer is caused by a genetic mutation that occurs during one person's…

Q: Describe the mutational event that produces the MYC oncogene in Burkitt’s lymphoma. Why does the…

A: Burkitt lymphoma is a type of non-Hodgkin lymphoma (NHL) that affects adults and children. NHL is…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.