Explain the difference between proto-oncogene and tumor suppressor mutations in terms of its potential to cause cancer.

Q: directly to DNA and plays a critical role in determining whether the DNA will be repaired or the…

A: p53 Mutations are a Frequent Event in Cancer:--The evolution in a normal cell producing cancerous…

Q: Describe three popular methods for silencing tumor-suppressor genes.

A: Introduction Tumor suppressor genes are those that slow down the division and development of cells.…

Q: Describe error prone polymerases and the process of translesion synthesis (TLS). In regards to tumor…

A: Translesion synthesis (TLS) is a method of overcoming stopped replication in which particular…

Q: Explain why p53 is mutated in the vast majority of human cancers.

A: Any isoform of a protein encoded by homologous genes in multiple animals, such as TP53 and Trp53, is…

Q: Metastasis occurs when cells from a primary tumor invade and colonize other tissues. Metastasis is a…

A: Metastasis is a critical process in cancer progression where cancer cells from a primary tumor site…

Q: Cellular levels of tumor suppressor protein p53 is maintained by a ubiquitin ligase protein, called…

A: From the above information, we can make the following inferences - 1. p53, as indicated in the…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.