Could a gene be involved in the growth of both stem cells and some kinds of cancer? Explain your answer.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Could a gene be involved in the growth of both stem cells and some kinds of cancer? Explain your answer.

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in stem cells we have an important class of genes called proto-oncogenes [PO] with are necessary for the proliferation and apoptosis of faulty cells.

when such genes become mutated they become oncogenes which are responsible for transforming the stem cell to cancer stem cells. these cells are capable of metastasis and reactivation of tumours in cured patients

along with PO, tumour suppressor genes are also required to ensure that the stem cell does not undergo uncontrolled proliferation on an oncogene is made  by mutations

 

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