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You decide to have your genome sequenced. The results come back and show that you have a gain-of-function mutation in a single copy of a proto-oncogene. Does this mean you are destined to get cancer? Yes, more than likely you will develop cancer. Not necessarily. You will only get cancer if the second copy of the gene also develops a loss-of-function mutation. Not necessarily. You will only get cancer if the second copy of the gene also develops a gain-of-function mutation. Not enough info to tell

You decide to have your genome sequenced. The results come back and show that you have a gain-of-function mutation in a single copy of a proto-oncogene. Does this mean you are destined to get cancer? Yes, more than likely you will develop cancer. Not necessarily. You will only get cancer if the second copy of the gene also develops a loss-of-function mutation. Not necessarily. You will only get cancer if the second copy of the gene also develops a gain-of-function mutation. Not enough info to tell

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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You decide to have your genome sequenced. The results come back and show that you have a gain-of-function mutation in a single copy of a proto-oncogene. Does this mean you are destined to get cancer? Yes, more than likely you will develop cancer. Not necessarily. You will only get cancer if the second copy of the gene also develops a loss-of-function mutation. Not necessarily. You will only get cancer if the second copy of the gene also develops a gain-of-function mutation. Not enough info to tell
Transcribed Image Text:You decide to have your genome sequenced. The results come back and show that you have a gain-of-function mutation in a single copy of a proto-oncogene. Does this mean you are destined to get cancer? Yes, more than likely you will develop cancer. Not necessarily. You will only get cancer if the second copy of the gene also develops a loss-of-function mutation. Not necessarily. You will only get cancer if the second copy of the gene also develops a gain-of-function mutation. Not enough info to tell
You decide to have your genome sequenced. The results come back and show that you have a loss-of-function mutation in a single copy of your p53 gene. Does this mean you are destined to get cancer? Yes, more than likely you will develop cancer. Not necessarily. You will only get cancer if the second copy of the gene also develops a loss-of-function mutation. Not necessarily. You will only get cancer if the second copy of the gene also develops a gain-of-function mutation. Not enough info to tell
Transcribed Image Text:You decide to have your genome sequenced. The results come back and show that you have a loss-of-function mutation in a single copy of your p53 gene. Does this mean you are destined to get cancer? Yes, more than likely you will develop cancer. Not necessarily. You will only get cancer if the second copy of the gene also develops a loss-of-function mutation. Not necessarily. You will only get cancer if the second copy of the gene also develops a gain-of-function mutation. Not enough info to tell
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