A. Which genes could be used to monitor the process of the disease? B.  If you worked for a drug company developing a treatment for the cancer, which genes would you target to turn on in cancer cells? C. Which genes would you target to turn off in cancer cells?

Human Anatomy & Physiology (11th Edition)
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A. Which genes could be used to monitor the process of the disease? B.  If you worked for a drug company developing a treatment for the cancer, which genes would you target to turn on in cancer cells? C. Which genes would you target to turn off in cancer cells?
1. After you identified several genes whose expression changes, you investigate their expression
during the course of the disease by taking mRNA samples from patients during four stages. The
expression pattern of 90% of the patients is shown in the following table. Light grey means the gene
is expressed at a low level and black means the gene is extremely active at that stage.
Stage 2
Gene
Annexin I
CD81 antigen
Maspin
Rho GDI
Fascin
Normal
Stage 1
Stage 3
Stage 4
Transcribed Image Text:1. After you identified several genes whose expression changes, you investigate their expression during the course of the disease by taking mRNA samples from patients during four stages. The expression pattern of 90% of the patients is shown in the following table. Light grey means the gene is expressed at a low level and black means the gene is extremely active at that stage. Stage 2 Gene Annexin I CD81 antigen Maspin Rho GDI Fascin Normal Stage 1 Stage 3 Stage 4
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