Which of the following statements concerning p53 is NOT correct? O a. O b. O C. p53-dependent transcription of target genes leads to cell cycle arrest or cell death (apoptosis). Loss of p53 function results in loss of checkpoint controls. Loss of p53 function creates an environment that is permissive for genome instability--that is, more damaged cells with chromosome aberrations and mutations survive and propagate. O d. p53 is a tumor suppressor protein which is largely responsible for protecting cells from cancer- causing DNA-damaging agents.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Which of the following statements
concerning p53 is NOT correct?
O a. p53-dependent transcription of target genes leads
to cell cycle arrest or cell death (apoptosis).
O b.
O C.
Loss of p53 function results in loss of checkpoint
controls.
Loss of p53 function creates an environment that
is permissive for genome instability--that is, more
damaged cells with chromosome aberrations and
mutations survive and propagate.
d. p53 is a tumor suppressor protein which is largely
responsible for protecting cells from cancer-
causing DNA-damaging agents.
Transcribed Image Text:Which of the following statements concerning p53 is NOT correct? O a. p53-dependent transcription of target genes leads to cell cycle arrest or cell death (apoptosis). O b. O C. Loss of p53 function results in loss of checkpoint controls. Loss of p53 function creates an environment that is permissive for genome instability--that is, more damaged cells with chromosome aberrations and mutations survive and propagate. d. p53 is a tumor suppressor protein which is largely responsible for protecting cells from cancer- causing DNA-damaging agents.
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