Occurred in her cells? (Unfortunately her parents have passed away.) I think these genes are inherited in autosmal dominant pattern, because a copy altered gene in each cell which is enough for a person to develop cancer. b. How could you use sequence analysis to determine if this gene is a tumor suppressor or an oncogene? (For partial credit briefly define tumor suppressor and oncogene.) Oncogenes are produced by activation, of proto oncogene, as for tumor repressor they casue cancer right when it is activated. Oncogene drive the cell cycle forward, tumor suppressor gene code for proteins that restrict cellualr grouth

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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(Just need part c) done with part a and b
Another cancer cell line that you are working on came from a patient in your medical clinic. You
recognize that this is a new type of breast cancer that has never been described before.
a. How could you use sequence analysis to determine if this patient inherited the mnutation
from one of her parents or if it spontaneously occurred in her cells? (Unfortunately her
parents have passed away.)
I think these genes are inherited in autosmal dominant pattern, because a
copy altered gene in each cell which is enough for a person to develop cancer.
b. How could you use sequence analysis to determine if this gene is a turnor suppressor or
an oncogene? (For partial credit briefly define tumor suppressor and oncogene.)
Oncogenes are produced by activation, of proto oncogene, as for tumor repressor they
casue cancer right when it is activated. Oncogene drive the cell cycle forward, tumor
suppressor gene code for proteins that restrict cellualr growth, which then can cause
apoptosis methylation.You could determine if gene is tumor represor or oncogeno by
using whole genome sequence method.
C. You determine that the mutation that is likely causing the patient's cancer in above
problem is the result of a change that generates an oncogene. How could you use
CRISPR/Cas9 and normal DNA repair to treat this patient? (Assume you can target
CRISPR/Cas9 to any cell you want in the patient.)
Transcribed Image Text:Another cancer cell line that you are working on came from a patient in your medical clinic. You recognize that this is a new type of breast cancer that has never been described before. a. How could you use sequence analysis to determine if this patient inherited the mnutation from one of her parents or if it spontaneously occurred in her cells? (Unfortunately her parents have passed away.) I think these genes are inherited in autosmal dominant pattern, because a copy altered gene in each cell which is enough for a person to develop cancer. b. How could you use sequence analysis to determine if this gene is a turnor suppressor or an oncogene? (For partial credit briefly define tumor suppressor and oncogene.) Oncogenes are produced by activation, of proto oncogene, as for tumor repressor they casue cancer right when it is activated. Oncogene drive the cell cycle forward, tumor suppressor gene code for proteins that restrict cellualr growth, which then can cause apoptosis methylation.You could determine if gene is tumor represor or oncogeno by using whole genome sequence method. C. You determine that the mutation that is likely causing the patient's cancer in above problem is the result of a change that generates an oncogene. How could you use CRISPR/Cas9 and normal DNA repair to treat this patient? (Assume you can target CRISPR/Cas9 to any cell you want in the patient.)
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