You are studying celiacs disease and have identified a potential gene for the disease using linkage analysis. You decide to test your hypothesis by making transgenic mice that carry a nonsense mutation in the candidate gene you have identified to see if they develop a phenotype similar to that found in Celiacs disease What sort or experimental approach are you using when you test your gene in your mouse model? a. Reverse genetic b. Quantitative genetic C. Forward genetic D.Expression analysis E. None of the above

Q: A mouse gene was identified and determined to be required for formation of heart muscle. A gene with…

A: Almost all species have DNA as their genetic material.

Q: The in situ hybridization method is based on Select one: a. labeling specific neuronal components…

A: Hybridization is the property of single-stranded nucleic acids to base-pair with their complementary…

Q: The figure below summarizes the results of an experiment evaluating the role of Ku80 gene DNA…

A: The gene knockout is performed for the detection of the role of a specific gene. The elimination of…

Q: The goal of most gene therapies is to insert a healthy copy of a gene into the genome.  Besides…

A: Genome editing:It is also known as gene editing or genome engineering. It is a type of genetic…

Q: The goal of most gene therapies is to insert a healthy copy of a gene into the genome.  Besides…

A: “Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: What is the expected frequency of the restriction site 5′−GGCC−3′ in a genome? A. Once every 4…

A:

Q: A B cat frame-shift no cat no cat cat nonsense cat C % survival 120 100 80 60 40 20 0 42 cat cats…

A: Fig 4: Panel A- Technique: Fluorescence microscopy has been used. All the 4 strains  are grown on in…

Q: ain A: wild type........ .CT value of 15 ain B: has mutation X in the promoter region........CT…

A: Quantitative reverse transcription polymerase chain reaction, also called RT-qPCR, is a molecular…

Q: We use the Alu element polymorphism to trace each student's ancestry. This element is present in an…

A: Introduction  Polymorphism refers to the occurrence of multiple genetic variants, or alleles, within…

Q: Which of the following approaches you can use to locate the relative positions of genes on…

A: Genes are located on chromosomes. These genes can not be targeted without using any specific gene…

Q: Based on the NCBI Blastp and reciprocal analysis, are there any mutations to suggest that mus…

A: In thе contеxt of tеsting thе human FGFR3 gеnе in Mus musculus, NCBI Blastp and rеciprocal analysis…

Q: What is knockdown gene analysis? How is this different from knockout analysis?

A: Gene knockdown is a method in which temporarily stop or decrease the expression of one or more…

Q: After performing analysis of whole genome sequencing from a candidate that grew on SC-H in the…

A: In genetic screening, a candidate that grows under specific conditions is analyzed to identify the…

Q: In this module, you have learned about the use of balancer chromosomes (such as TM2 and TM6C in the…

A: Lethal genes are alleles that result in an end of the entity that possesses them. In basic terms,…

Q: RNAi is a method to assess........ gene expression    gene sequence  gene function  Chromosomal…

A: A gene is a functioning heredity unit made up of DNA, which provides instructions for the creation…

Q: E. coli strain BW25113 can grow on (D) Arg as the sole carbon source. A scientist  working with you…

A: Obtain the genomic  from the mice cells that encode for the protease of interest.Fragment the…

Q: From gene expression studies on cancer, you discovered a hypothetical gene called ABCG2 that is…

A: Transgenic approach has been proved to be very useful in studying physiological function of a…

Q: You are tasked with amplifying a gene of interest with PCR. a. After performing a Southern blot, you…

A: Polymerase Chain Reaction(PCR)  is a technique used to  amplify the number of DNA or RNA strands.…

Q: The goal of most gene therapies is to insert a healthy copy of a gene into the genome.  Besides…

A: The genome of an organism is defined as the whole genetic information that is inherited from one…

Q: assess anatomical distribution of gene expression.   genomic pcr nortbern blotting Rnai in situ…

A: The genes are the functional part of the DNA that undergoes transcriptional process and ultimately…

Q: When bacteria are consumed by macrophages, the macrophages give off chemokines that recruit other…

A: Chemokines have many different activities, and in many cases, the microenvironment has a significant…

Q: If a mutation in a homeotic gene produced the following phenotypes, would you expect it to be a…

A: Mutation refers to the sudden changes that occur in the sequence of DNA’s (deoxyribonucleic acid)…

Q: Introducing a specific change in the mouse genome using CRISPR/Cas9 requires: a. Alterations to both…

A: CRISPR based genome editing is widely applied in the field of biotechnology, medicine, genomic…

Q: Based on recent data arising from various animal models, which of the following CRISPR-Cas9 systems…

A: based on recent data arising from various animal models, A. CRISPR-dCas9 systems would be the most…

Q: Based on Pruisner (2013), match each of the following terms with its appropriate definition or…

A: Genes are sequences of DNA present in the chromosome of an organism that code for certain…

Q: SIM is toxic to E. coli. Ali has discovered that a novel prokaryote, C.bantaglia genome encodes for…

A: A. Steps to Construct the Genomic Library for Recombinant Expression in E. coli:1. **Isolation of…

Q: Identify the best match between the mutation description and term.   a. Transversion: results in a…

A: Often mutation occurs in our body. These mutations can be beneficial or lethal. The mutation occurs…

Q: What does it mean for a transposable element to be effectively “dead”? A. The transposable elements…

A: A transposable element is a DNA sequence that can change its position within a genome

Communication

Communication is a method of transferring information between two persons or organisms. Communication is possible using mutually understood behaviors such as signs, symbols, or language. In the year 1980, S. F. Scudder proposed communication theory. According to his ideas, all living beings on the earth communicate, but the methods of communication differ. Communication skills are now part of soft skills.