SCENARIO: You are studying a disease caused when the gene called BMP5 is not transcribed in osteoblasts. All other genes are transcribed normally. To investigate why BMP5 is not transcribed, you create a reporter transgene by putting GFP under the control of the BMP5 enhancer found in diseased osteoblasts. You put this reporter transgene into a normal, healthy osteoblast. ----------------- Short Answer Question 4: In the question above, does it matter if the BMP5 enhancer-GFP reporter gene is tested in a normal, healthy osteoblast or in a diseased osteoblast? Why or why not?
SCENARIO: You are studying a disease caused when the gene called BMP5 is not transcribed in osteoblasts. All other genes are transcribed normally. To investigate why BMP5 is not transcribed, you create a reporter transgene by putting GFP under the control of the BMP5 enhancer found in diseased osteoblasts. You put this reporter transgene into a normal, healthy osteoblast. ----------------- Short Answer Question 4: In the question above, does it matter if the BMP5 enhancer-GFP reporter gene is tested in a normal, healthy osteoblast or in a diseased osteoblast? Why or why not?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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SCENARIO: You are studying a disease caused when the gene called BMP5 is not transcribed in osteoblasts. All other genes are transcribed normally. To investigate why BMP5 is not transcribed, you create a reporter transgene by putting GFP under the control of the BMP5 enhancer found in diseased osteoblasts. You put this reporter transgene into a normal, healthy osteoblast.
-----------------
Short Answer Question 4: In the question above, does it matter if the BMP5 enhancer-GFP reporter gene is tested in a normal, healthy osteoblast or in a diseased osteoblast? Why or why not?
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