You discover a histone variant that has more positive charge than conventional histone proteins.What effect do you predict this histone variant would have when it is inserted into chromatin?A decrease in the strength of histone-DNA interaction, making chromatin less condensed and increasing geneexpressionAn increase in the strength of histone-DNA interaction, making chromatin less condensed and decreasing geneexpressionAn increase in the strength of histone-DNA interaction, making chromatin more condensed and decreasing geneexpressionO A decrease in the strength of histone-DNA interaction, making chromatin less condensed and decreasing geneexpression

Answer: Histones are the octamer protein which has been wrapped by the DNA forming strong…

Answered: What effect do you predict this histone…

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What effect do you predict this histone variant would have when it is inserted into chromatin?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter8: The Structure, Replication, And Chromosomal Organization Of Dna

Section: Chapter Questions

Problem 25QP: Discuss the levels of chromosomal organization with reference to the following terms: a. nucleotide...

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Discuss the levels of chromosomal organization with reference to the following terms: a. nucleotide b. DNA double helix c. histones d. nucleosomes e. chromatin
Chromatin decompaction is a preliminary step in gene expression (Figure 29.48). How is chromatin decompacted?
Define the following terms: a. chromosome b. chromatin
Give examples of the different classes of mutations that affect the base sequence of DNA in protein encoding genes and explain the effects that each has on the polypeptide produced.
Biologists have long been interested in the effects of radiation on cells. In one experiment, researchers examined the effect of radium on mitosis of chick embryo cells growing in culture. A population of experimental cells was examined under the microscope for the number of cells in telophase (as a measure of mitosis occurring) before, during, and after exposure to radium. The results are shown in the Figure. What is the effect of radium exposure on mitosis? Source: R. G. Canti and M. Donaldson. 1926. The effect of radium on mitosis in vitro. Proceedings of the Royal Society of London, Series B, Containing Papers of a Biological Character 100:413419.
Some autoimmune diseases show a positive correlation with dramatically decreased expression of histone deacetylase 9 (HDAC9, an enzyme that removes acetyl groups from histones). Why would the decreased expression of HDAC9 cause immune cells to produce inflammatory genes at inappropriate times?
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How many autosomes are present in a body cell of a human being? In a gamete?
Figure 16.7 In females, one of the two X chromosomes is inactivated during embryonic development because of epigenetic changes to the chromatin. What impact do you think these changes would have on nucleosome packing?
Discuss Concepts The normal form of a gene contains the nucleotide sequence: When this gene is transcribed, the result is the following mRNA molecule: In a mutated form of the gene, two extra base pairs (underlined) are inserted: What effect will this particular mutation have on the structure of the protein encoded in the gene?
In eukaryotic chromosomes, DNA wraps around _________. a. histone proteins c. centromeres b. sister chromatids d. nucleosomes
If the coding region of a gene (the exons) contains 2,100 base pairs of DNA, would a missense mutation cause a protein to be shorter, longer, or the same length as the normal 700 amino acid proteins? What would be the effect of a nonsense mutation? A sense mutation?