The most prominent mutation of ERBB2 in breast cancer is L755S.  What kind of mutation is this?  Is this a driver or passenger mutation? How to do you know?

Q: Which natural genetic mechanism is responsible for preventing the expression of genes that are…

A: DNA is made up of numerous molecules known as nucleotide. A non-sense mutation is a type of mutation…

Q: Inversion of an enhancer region does not affect gene expression, but inversion of the promoter…

A: Key references:Bozhilov, Y. K., Downes, D. J., Telenius, J., Marieke Oudelaar, A., Olivier, E. N.,…

Q: Insulin is a peptide hormone encoded by the INS gene, which is on chromosome 11. Insulin is produced…

A: The hormone insulin is required by the body to reduce the level of blood glucose. The pancreatic…

Q: How many of the mutations listed below would lead to excessive cell growth when the cell was either…

A: Excessive growth occurs when a cell continuously divides and when there is no cell cycle arrest. Myc…

Q: What is the effect of supper repressor (lacI^s) mutations?

A: Lac operon is a transcriptionally regulated system in E.coli which enables the bacteria to utilize…

Q: Some mutations in the trp 5′ UTR increase termination by the attenuator. Where might these mutations…

A: Tryptophan operon consists of a leader region located at the 5' terminal of mRNA called 5' UTR. The…

Q: How do draw the sequence in this question? Draw the sequence of molecular events that occurs to…

A: STAT (signal transducer and activator of transcription) protein family are transcription factors…

Q: What is a CpG island? Where would you expect one to be located? How does the methylation of CpG…

A: A gene is a stretch of nucleotides present in the DNA. DNA or deoxyribonucleic acid is a polymer of…

Q: One mutation is a deletion of six nucleotides in the second exon of the gene and the other mutation…

A: Introns and exons are nucleotide sequences within a gene in mRNA. The conversion of DNA to RNA is…

Q: In a qPCR experiment, you find that the mRNA for the gene CDK1 goes down (decreased expression) when…

A: qPCR (quantitative polymerase chain reaction), also known as real-time PCR, is a laboratory…

Q: A gene, which we will call gene C, can be epigenetically modified in such a way that its expression…

A: Introduction: Gene is the structural and functional unit of inheritance or heredity which transfers…

Q: What happens if there is too much p16-ink4a in a juvenile and elderly human? what happens if a…

A: Introduction:- The unregulated and abnormal proliferation of normal cells results into the formation…

Q: Methylation of H3K9 by itself silences genes, but if H3K4 and H4K20 are also methylated, the…

A: Histones are the basic proteins that are employed in nucleosome formation during the chromatin…

Q: Do you think there are more unique alleles of p53 that lead to cancer or more unique alleles of Ras…

A:

Q: Organisms must rapidly acclimate to changes in their environment. For instance, temperature changes…

A: Octopus bimaculoides often called "bimac" is an octopus species that belongs to class cephalopoda.…

Q: If p63 can bind to the same promoter elements as p53, why would it be considered an inhibitor of…

A: Promoters are DNA sequences that function as a kind of "On" switch to start the biological process…

Q: How do I draw the sequence and explain the process for each step? Draw the sequence of molecular…

A: In the nucleus, the STAT dimers localise and bind to specific DNA targets and induce gene…