In general MHC 1 receptors harboring antigen are recognized by the CD-8 receptor on T-cells; furthermore, MHC 2 receptors harboring antigen are recognized by CD-4 receptor on T-cells. What is the significance of this specific interaction between these different cells types? A. CD-4 and CD-8 markers are found on T-helper and T-cytotoxic cells, respectively, and these two proteins are responsible for mediating self-recognition between antigen presenting cells and T-cells by binding a specific epitope on their cognate MHC receptor complex. B. Both CD-4 and CD-8 are responsible for controlling and mediating the secretion of cytokines by T-cells. C. Professional Macrophages expressing MHC 2 complex and other cells that express MHC 1 complex bind CD-4 and CD-8 respectively, but the interaction between these immune cells are inconsequential. D. None of the above are significant or correct.

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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In general MHC 1 receptors harboring antigen are recognized by the CD-8 receptor on T-cells;
furthermore, MHC 2 receptors harboring antigen are recognized by CD-4 receptor on T-cells. What
is the significance of this specific interaction between these different cells types?
A. CD-4 and CD-8 markers are found on T-helper and T-cytotoxic cells, respectively, and these two
proteins are responsible for mediating self-recognition between antigen presenting cells and T-cells
by binding a specific epitope on their cognate MHC receptor complex.
B. Both CD-4 and CD-8 are responsible for controlling and mediating the secretion of cytokines by
T-cells.
C. Professional Macrophages expressing MHC 2 complex and other cells that express MHC 1
complex bind CD-4 and CD-8 respectively, but the interaction between these immune cells are
inconsequential.
D. None of the above are significant or correct.
Transcribed Image Text:In general MHC 1 receptors harboring antigen are recognized by the CD-8 receptor on T-cells; furthermore, MHC 2 receptors harboring antigen are recognized by CD-4 receptor on T-cells. What is the significance of this specific interaction between these different cells types? A. CD-4 and CD-8 markers are found on T-helper and T-cytotoxic cells, respectively, and these two proteins are responsible for mediating self-recognition between antigen presenting cells and T-cells by binding a specific epitope on their cognate MHC receptor complex. B. Both CD-4 and CD-8 are responsible for controlling and mediating the secretion of cytokines by T-cells. C. Professional Macrophages expressing MHC 2 complex and other cells that express MHC 1 complex bind CD-4 and CD-8 respectively, but the interaction between these immune cells are inconsequential. D. None of the above are significant or correct.
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