Why do you think antibodies against the N-terminal domain (NTD) provide protection against SARS-CoV2 when the NTD does not interact with the ACE2 receptor? Question 23 options: Binding causes steric hindrance of ACE2 to the receptor binding domain (RBD). Antibodies interact with antigens using a lock-and-key interaction Antibodies against the NTD recruit antibodies against the receptor binding domain (RBD). Antibodies against the NTD are not protective. Binding causes a conformational change in the RBD domain.
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
Why do you think antibodies against the N-terminal domain (NTD) provide protection against SARS-CoV2 when the NTD does not interact with the ACE2 receptor?
Question 23 options:
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Binding causes steric hindrance of ACE2 to the receptor binding domain (RBD). |
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Antibodies interact with antigens using a lock-and-key interaction |
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Antibodies against the NTD recruit antibodies against the receptor binding domain (RBD). |
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Antibodies against the NTD are not protective. |
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Binding causes a conformational change in the RBD domain. |
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