Based on these data, where would you MOST likely find toll-like receptor-XX (TLR-XX) among the following options? Justify WHY you selected that option.Your justification must be based on the data that are presented here, not the type of bacteria. A. On the cell surface B. In the endosome/ lysosome C. In the nucleus D. In the mitochondria E. In the endoplasmic reticulum
Based on these data, where would you MOST likely find toll-like receptor-XX (TLR-XX) among the following options? Justify WHY you selected that option.Your justification must be based on the data that are presented here, not the type of bacteria. A. On the cell surface B. In the endosome/ lysosome C. In the nucleus D. In the mitochondria E. In the endoplasmic reticulum
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter12: Body Defenses
Section: Chapter Questions
Problem 6RE
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Question
Based on these data, where would you MOST likely find toll-like receptor-XX (TLR-XX) among the following options? Justify WHY you selected that option.Your justification must be based on the data that are presented here, not the type of bacteria.
A. On the cell surface
B. In the endosome/ lysosome
C. In the nucleus
D. In the mitochondria
E. In the endoplasmic reticulum
![cytochalasin B
Killed bacteria + cytochalasin B
killed bacteria
Live bacteria
No treatment
0
III.
20
40
60
Amount of IL-2 Produced (mg)
The graph shown above shows data generated by
exposing TLR-XX-expressing macrophages to
Gram negative bacteria (Staph. sp.) that possess
lipopolysaccharides (LPS) on their surface. These
bacteria have been inactivated (killed) by heat
treatment or added alive. These experimental
treatments were performed in the presence or
absence of cytochalasin B, which is a chemical
that prevents phagocytosis. Note that TLR-X +
hypothetical tool-like receptor.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fd86e2176-2b92-4a94-a128-f6a0aba0ae4d%2F9d8526dc-83ec-4c63-814e-108509e411c5%2Fty1k8fk_processed.jpeg&w=3840&q=75)
Transcribed Image Text:cytochalasin B
Killed bacteria + cytochalasin B
killed bacteria
Live bacteria
No treatment
0
III.
20
40
60
Amount of IL-2 Produced (mg)
The graph shown above shows data generated by
exposing TLR-XX-expressing macrophages to
Gram negative bacteria (Staph. sp.) that possess
lipopolysaccharides (LPS) on their surface. These
bacteria have been inactivated (killed) by heat
treatment or added alive. These experimental
treatments were performed in the presence or
absence of cytochalasin B, which is a chemical
that prevents phagocytosis. Note that TLR-X +
hypothetical tool-like receptor.
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