n ligand binds to a ligand gates ce closes e opens ns flow through gate is released

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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The document contains a series of multiple-choice questions related to biological concepts, particularly focusing on cellular responses and protein mutations. Below is the transcribed content:

---

**23) Based on the conserved evolution of signal transduction pathways and the specificity of receptors for ligands, tests were performed that show:**

A) Human cells in vitro cultured respond to bovine (cow) hormones  
B) Animal cells can respond to hormones made from bacteria  
C) Yeast cells use mating-type signal to locate mates and respond by making protist cells  
D) Plant hormones have a significant impact on the animals that eat them

**24) RAS mutants occur in one-third of all cancers. RAS is a kinase that cross talks with cell growth and apoptosis pathways. When we say RAS mutants are resistant to chemotherapy, that means:**

A) RAS protein inactivate drugs used in chemotherapy  
B) Drugs that should cause apoptosis fail in mutations in RAS mutant cells  
C) Chemotherapy cannot improve the DNA mutations in RAS mutant cells  
D) RAS phosphorylates the drugs used in chemotherapy

**25) When a ligand binds to a ligand-gated ion channel receptor, what order of operations occurs?**

I. Gate closes  
II. Gate opens  
III. Ions flow through gate  
IV. Ligand is released  

A) I, II, III, IV  
B) II, III, IV, I  
C) III, II, IV, I  
D) IV, III, II, I

---

This document section does not contain graphs or diagrams. It focuses on biological concepts pertinent to cell biology and protein functionality, likely for educational purposes.
Transcribed Image Text:The document contains a series of multiple-choice questions related to biological concepts, particularly focusing on cellular responses and protein mutations. Below is the transcribed content: --- **23) Based on the conserved evolution of signal transduction pathways and the specificity of receptors for ligands, tests were performed that show:** A) Human cells in vitro cultured respond to bovine (cow) hormones B) Animal cells can respond to hormones made from bacteria C) Yeast cells use mating-type signal to locate mates and respond by making protist cells D) Plant hormones have a significant impact on the animals that eat them **24) RAS mutants occur in one-third of all cancers. RAS is a kinase that cross talks with cell growth and apoptosis pathways. When we say RAS mutants are resistant to chemotherapy, that means:** A) RAS protein inactivate drugs used in chemotherapy B) Drugs that should cause apoptosis fail in mutations in RAS mutant cells C) Chemotherapy cannot improve the DNA mutations in RAS mutant cells D) RAS phosphorylates the drugs used in chemotherapy **25) When a ligand binds to a ligand-gated ion channel receptor, what order of operations occurs?** I. Gate closes II. Gate opens III. Ions flow through gate IV. Ligand is released A) I, II, III, IV B) II, III, IV, I C) III, II, IV, I D) IV, III, II, I --- This document section does not contain graphs or diagrams. It focuses on biological concepts pertinent to cell biology and protein functionality, likely for educational purposes.
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