The activity provides you with a version of the NGF pathway, an example of a RTK. All of the proteins involved can be in ON/OFF states. Using this cell signaling pathway you will be asked a variety of questions to determine how the molecules are regulated, but also how a cell would respond if this cell signaling party steps vere interrupted or activated.
The activity provides you with a version of the NGF pathway, an example of a RTK. All of the proteins involved can be in ON/OFF states. Using this cell signaling pathway you will be asked a variety of questions to determine how the molecules are regulated, but also how a cell would respond if this cell signaling party steps vere interrupted or activated.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:The activity provides you with a version of the NGF pathway, an example of a RTK. All of the proteins
involved can be in ON/OFF states. Using this cell signaling pathway you will be asked a variety of questions to
determine how the molecules are regulated, but also how a cell would respond if this cell signaling party steps
were interrupted or activated.
Neural Growth
Factir (NGF)
Ras-
Ras-
GDP
GTP
Trk-A
Ras-GEF
braf
braf
МЕК
МЕК
ERK
ERK
ERK
ERK
STAT
STAT
Spiouty DNA
Nucleus
Cytosol

Transcribed Image Text:The Pathway presented shows you how the pathway is regulated with a Ras-GEF. Explain how adding a Ras-GAP to
the cell would A) specifically affect the molecules of the signaling pathway and B) affect the response of the cell.
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