Cells migrate by interacting with the extracellular matrix via the binding of membrane integrin with in the ECM. proteoglycans B) vinculin fibronectin collagen microfilaments

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Question:**
Cells migrate by interacting with the extracellular matrix via the binding of membrane integrin with __________ in the ECM.

**Options:**
- A) proteoglycans
- B) vinculin
- C) fibronectin
- D) collagen
- E) microfilaments

**Summary:**
This question examines the interaction between cell surface receptors, specifically integrins, and components of the extracellular matrix (ECM) that facilitate cell migration. Understanding the specific binding partners within the ECM is crucial for comprehending cell movements and influences on cell behavior in various biological and pathological contexts.
Transcribed Image Text:**Question:** Cells migrate by interacting with the extracellular matrix via the binding of membrane integrin with __________ in the ECM. **Options:** - A) proteoglycans - B) vinculin - C) fibronectin - D) collagen - E) microfilaments **Summary:** This question examines the interaction between cell surface receptors, specifically integrins, and components of the extracellular matrix (ECM) that facilitate cell migration. Understanding the specific binding partners within the ECM is crucial for comprehending cell movements and influences on cell behavior in various biological and pathological contexts.
**Question:**

In which of the following signaling pathways does ligand binding induce the phosphorylation of the receptor molecules? (Check all that apply.)

**Options:**

A. The TGF-beta pathway.

B. The Hedgehog/smoothened pathway.

C. The Notch/Delta pathway.

D. The Receptor-tyrosine kinase pathway.

E. The canonical Wnt pathway.

---

This question focuses on signaling pathways and their mechanisms involving receptor phosphorylation in response to ligand binding. The options explore various well-known biological pathways, asking for identification of those involving receptor phosphorylation events.
Transcribed Image Text:**Question:** In which of the following signaling pathways does ligand binding induce the phosphorylation of the receptor molecules? (Check all that apply.) **Options:** A. The TGF-beta pathway. B. The Hedgehog/smoothened pathway. C. The Notch/Delta pathway. D. The Receptor-tyrosine kinase pathway. E. The canonical Wnt pathway. --- This question focuses on signaling pathways and their mechanisms involving receptor phosphorylation in response to ligand binding. The options explore various well-known biological pathways, asking for identification of those involving receptor phosphorylation events.
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