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For immunoglobulin heavy and light chain genes, and for T-cell receptor b chain genes, there are a large number of V gene segments, and relatively few J and/or D segments that rearrange to form the final coding sequence for each gene. The TCR a locus is different in this regard, and this difference is thought to reflect the fact that nearly all a:b T-cell receptors recognize a peptide bound to an MHC molecule. This unique feature of the T-cell receptor a locus is: The presence of only five different Va gene segments The presence of two different Ca coding sequences The presence of over sixty different Ja gene segments The absence of D gene segments The large sequence distance separating the Va gene segments from the Ja gene segments

For immunoglobulin heavy and light chain genes, and for T-cell receptor b chain genes, there are a large number of V gene segments, and relatively few J and/or D segments that rearrange to form the final coding sequence for each gene. The TCR a locus is different in this regard, and this difference is thought to reflect the fact that nearly all a:b T-cell receptors recognize a peptide bound to an MHC molecule. This unique feature of the T-cell receptor a locus is: The presence of only five different Va gene segments The presence of two different Ca coding sequences The presence of over sixty different Ja gene segments The absence of D gene segments The large sequence distance separating the Va gene segments from the Ja gene segments

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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For immunoglobulin heavy and light chain genes, and for T-cell receptor b chain genes, there are a large number of V gene segments, and relatively few J and/or D segments that rearrange to form the final coding sequence for each gene. The TCR a locus is different in this regard, and this difference is thought to reflect the fact that nearly all a:b T-cell receptors recognize a peptide bound to an MHC molecule. This unique feature of the T-cell receptor a locus is:

  1. The presence of only five different Va gene segments
  2. The presence of two different Ca coding sequences
  3. The presence of over sixty different Ja gene segments
  4. The absence of D gene segments
  5. The large sequence distance separating the Va gene segments from the Ja gene segments
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