Which of the following would most likely mimic Rb loss? Rb mutant where the phosphosites are mutated to alanine G1 cyclin with a shorter half-life Constitutively active E2F Ras GTPase mutant with increased hydrolysis activity
Which of the following would most likely mimic Rb loss? Rb mutant where the phosphosites are mutated to alanine G1 cyclin with a shorter half-life Constitutively active E2F Ras GTPase mutant with increased hydrolysis activity
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Transcribed Image Text:Which of the following would most likely mimic Rb loss?
Rb mutant where the phosphosites are mutated to alanine
G1 cyclin with a shorter half-life
Constitutively active E2F
Ras GTPase mutant with increased hydrolysis activity
Loss of Ras-GEF
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