Mice lacking IL-15 or the IL-15Ra chain have substantially reduced numbers of type b IELS, including both a:B and y:ó T-cell receptor-positive subsets. Normal numbers of type b IELS can be restored in il15/- mice by cell-type specific expression of JL-15 in Thymic cortical epithelial cells O Thymic medullary epithelial cells O Dendritic cells O Intestinal epithelial cells
Mice lacking IL-15 or the IL-15Ra chain have substantially reduced numbers of type b IELS, including both a:B and y:ó T-cell receptor-positive subsets. Normal numbers of type b IELS can be restored in il15/- mice by cell-type specific expression of JL-15 in Thymic cortical epithelial cells O Thymic medullary epithelial cells O Dendritic cells O Intestinal epithelial cells
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:Mice lacking IL-15 or the IL-15RA chain have substantially reduced numbers of type b IELS, including both a:B and y:ó T-cell receptor-positive
subsets. Normal numbers of type b IELS can be restored in il15/- mice by cell-type specific expression of JL-15 in
O Thymic cortical epithelial cells
O Thymic medullary epithelial cells
Dendritic cells
O Intestinal epithelial cells
Mice deficient in the enzyme MMP7, that cleaves prepro-a-defensin to the active a-defensin, show an increased susceptibility to the entenc
pathogen, Salmonella typhimurium. The cell type in the gastrointestinal (GI) epithelium most likely to express the highest ieveis of MMP7 I.
O M cells
O Paneth cells
Intraepithelial lymphocytes
O Goblet cells
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