Antigen recognition by T cells in the absence of co-stimulation results in a. upregulation of B7 b. expression of the high-affinity IL-2 receptor c. T-cell anergy d. T-cell apoptosis e. phosphorylation of immunoreceptor tyrosine-based activation motifs.

Antigen recognition by T cells in the absence of co-stimulation results in a. upregulation of B7 b. expression of the high-affinity IL-2 receptor c. T-cell anergy d. T-cell apoptosis e. phosphorylation of immunoreceptor tyrosine-based activation motifs.

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter12: Body Defenses

Section: Chapter Questions

Problem 15RE

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Concept explainers

Immunology

Immunology is the division of science involved with the immune reactions occurring in living organisms. The organisms are accustomed to evolving internal defense mechanisms to evade the invasion of microbial pathogens. Diverse cells are connected with stimulating the immune responses, which produce inhospitable conditions to the microbes prompting their lysis and thus inhibits the multiplication of the pathogens. The immune system can distinguish the pathogens through the aid of cellular intercommunication and launch responses to destroy them.

Question

Antigen recognition by T cells in the absence of co-stimulation results in

a. upregulation of B7

b. expression of the high-affinity IL-2 receptor

c. T-cell anergy

d. T-cell apoptosis

e. phosphorylation of immunoreceptor tyrosine-based activation motifs.

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