1. Which of the following statements about CD4+ Th17 cells are true?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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1. Which of the following statements about CD4+ Th17 cells are true?

i. Cannot form T effector memory (TEM) T cell populations

ii. Require the master transcription factor RORgammaT for their development

iii. Produce effector cytokines IL-17 and IL-22 which help recruit neutrophils and stimulate antimicrobial peptide production

iv. Do not require the transcription factor NFAT for IL-2 production downstream of TCR activation

v. Important for defense against intracellular bacterial infection only


a. i and iii
b. ii and v
c. ii and iii
d. ii, iii, iv
e. i, ii, and iv
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