Class switching is initiated by T-cell activation via CD40 ligation. You are working with a mouse model that is deficient in CD40L. What kind of phenotype would you expect to see in the mouse? a lack of memory T cells O a lack of antibodies of classes other than IgM O extremely high concentrations of IgE O extremely low concentrations of IgD

Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter42: The Immune System
Section: Chapter Questions
Problem 1VCQ: Figure 42.11 Which of the following statements about T cells is false? Helper T cells release...
Question
Class switching is initiated by T-cell activation via CD40 ligation. You are working with a mouse model that is deficient in CD40L. What
kind of phenotype would you expect to see in the mouse?
a lack of memory T cells
a lack of antibodies of classes other than IgM
extremely high concentrations of IgE
extremely low concentrations of IgD
Transcribed Image Text:Class switching is initiated by T-cell activation via CD40 ligation. You are working with a mouse model that is deficient in CD40L. What kind of phenotype would you expect to see in the mouse? a lack of memory T cells a lack of antibodies of classes other than IgM extremely high concentrations of IgE extremely low concentrations of IgD
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